| case | 1. An instance of disease with its attendant circumstances. Compare: patient. 2. A box or container. Origin: L. Casus, an occurrence Borderline case, a patient, whose clinical findings are suggestive, but not fully convincing, of a specific diagnosis. (05 Mar 2000) |
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| case-control study | <epidemiology> A study in which the risk factors of people with a disease are compared with those without a disease. It is an epidemiological method that begins by identifying persons with the disease or condition of interest (the cases) and compares their past history of exposure to identified or suspected risk factors with the past history of similar exposures among persons who resemble the cases but do not have the disease or condition of interest (the controls). The relationship of an attribute to the disease can therefore be examined by comparing affected and non-affected individuals with regard to the frequency or levels of the attribute in each group. (05 May 2002) |
| case fatality rate | The proportion of individuals contracting a disease that die of that disease. (05 Mar 2000) |
| case fatality ratio | The mortality rate of a disease, usually expressed per 100 cases. (05 Mar 2000) |
| case management | A traditional term for all the activities which a physician or other health care professional normally performs to insure the coordination of the medical services required by a patient. It also, when used in connection with managed care, covers all the activities of evaluating the patient, planning treatment, referral, and follow-up so that care is continuous and comprehensive and payment for the care is obtained. (12 Dec 1998) |
| index case | A person who first draws attention to their family. For example, if my eye doctor discovers i have glaucoma and subsequently other cases of glaucoma are found in my family, i am the index case. Also called the propositus (if male) or proposita (if female). (12 Dec 1998) |
| organizational case studies | Descriptions and evaluations of specific health care organizations. (12 Dec 1998) |
| trial case | In refraction, a box containing lenses for testing. (05 Mar 2000) |
| fly-case | <entomology> The covering of an insect, especially. The elytra of beetles. Source: Websters Dictionary (01 Mar 1998) |
| aphasia, primary progressive | A type of aphasia appearing gradually and gradually worsening without any major change in other cognitive functions. It is regarded by some authors as a syndrome which may be due to various degenerative diseases of the cerebral cortex (notably alzheimer disease, owing to its frequency), while others see in it an autonomous disease related to a neuropathological process that is distinct from the main degenerative dementias. The principal clinical peculiarity of primary progressive aphasia is that it spares the patient's autonomy for a long time, but ultimately turns into global dementia. (12 Dec 1998) |
| bovine progressive degenerative myeloencephalopathy | A familiar myeloencephalopathy of brown Swiss cattle characterised by bilateral hindleg weakness and ataxia and deficient proprioceptive reflexes. (05 Mar 2000) |
| rapidly progressive glomerulonephritis | <nephrology> A relatively uncommon (affecting 1 out of 10,000 people) form of acute glomerulonephritis that results in damage within the glomerulus of the kidney. There is rapid loss of kidney function with the formation of crescents on microscopic analysis (kidney biopsy). This disorder may result in acute glomerulonephritis or nephrotic syndrome, but ultimately results in renal failure and end-stage renal disease. Symptoms include smoky coloured urine (pyuria), decreased urine output, swelling and hypertension. Any conditions which can cause a vasculitis increase the risk of this disorder. Some examples include lupus, Goodpasture's syndrome, Henoch-Schonlein purpura, IgA nephropathy, membranoproliferative glomerulonephritis, anti-glomerular basement membrane antibody disease, history for malignant tumours and exposure to hydrocarbon solvents. (27 Sep 1997) |
| chronic progressive chorea | A progressive disorder usually beginning in young to middle age, consisting of a triad of choreoathetosis, dementia, and autosomal dominant inheritance with complete penetrance. Bilateral marked wasting of the putamen and the head of the caudate nucleus is characteristic. Synonym: chronic progressive chorea, degenerative chorea, hereditary chorea, Huntington's disease. (05 Mar 2000) |
| chronic progressive external ophthalmoplegia | A specific type of slowly worsening weakness of the ocular muscles, usually associated with a pigmentary retinopathy. See: Kearns-Sayre syndrome, oculopharyngeal dystrophy. Synonym: ocular myopathy. (05 Mar 2000) |
| chronic progressive syphilitic meningoencephalitis | Syphilitic infection manifested as dementia (often with delusional features), dysarthria, seizures, myoclonic jerks, action tremor, impaired walking and standing, pupillary abnormalities, and abnormal CSF findings. Synonym: chronic progressive syphilitic meningoencephalitis. (05 Mar 2000) |