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progabide (4-[(4-chlorophenyl, 5-fluoro-2-hydroxyphenyl) methylene]amino-butabeamide;an anticonvulsant which is a lipid-soluble derivative of the amidated form of gamma-aminobutyric acid (GABAmide) that, unlike gamma-aminobutyric acid (GABA) itself, is able to cross the blood-brain barrier. Once inside the brain the drug is converted to several metabolites, some of which are active forms of GABA or related compounds which act on GABA receptors to increase inhibition in the brain.
(05 Mar 2000)
progastrin Precursor of gastric secretion in the mucous membrane of the stomach.
(05 Mar 2000)
progelatinase <enzyme> Mw 72 kD; tissue inhibitor of metalloproteinase-2 binds to stabilization site, thereby preventing autocatalytic activation and degradation but not gelatinolysis by the enzyme-inhibitor complex
Registry number: EC 3.4.24.-
Synonym: gelatinase precursor, progelatinase a, progelatinase b, prommp-2
(26 Jun 1999)
progenia Synonym: prognathism.
Origin: pro-+ L. Gena, cheek
(05 Mar 2000)
progenitalis <virology> A group of acute infections causes by herpes simplex virus type 1 or type 2, characterised by the development of one or more small fluid filled vesicles with a raised erythematous base on the skin or mucous membrane and occurring as a primary infection or recurring because of reactivation of a latent infection. Type 1 infections usually involve nongenital regions of the body, whereas in type 2 infections the lesions are primarily seen on the genital and surrounding areas. Precipitating factors include fever, exposure to cold temperature or to ultraviolet rays, sunburn, cutaneous or mucosal abrasions, emotional stress and nerve injury.
(18 Nov 1997)
progenitor A precursor, ancestor; one who begets.
Origin: L.
(05 Mar 2000)
progenitor cell <cell biology> In development a parent cell that gives rise to a distinct cell lineage by a series of cell divisions.
(18 Nov 1997)
progenitor cell transplant (stem cell transplant, blood cell transplant): The transplantion of parent cells which may give rise to progeny (daughter cells) which erve more specialised functions. Transplants may be from the peripheral blood or bone marrow. The patient himself/herself may be the donor (autologous transplant), a (genetically) compatible relative or individual (allogeneic transplant).
(16 Dec 1997)
progenitress A female progenitor.
Source: Websters Dictionary
(01 Mar 1998)
progeny Offspring; descendants.
Origin: L. Progenies, fr. Progigno, to beget
(05 Mar 2000)
progeria <syndrome> Accelerated aging syndrome in which most of the characteristic stages of human senescence are compressed into less than a decade. Defect probably in DNA repair.
(18 Nov 1997)
progeria with cataract A syndrome of bony anomalies of the calvaria, face, and jaw, with brachygnathia, narrow curved nose, and multiple ocular defects including microphthalmia, microcornea, and cataract, often with alopecia overlying skull sutures, or alopecia areata and hypoplasia, or absence of eyebrows. The pattern of inheritance is undecided.
Synonym: congenital sutural alopecia, Hallermann-Streiff syndrome, Hallermann-Streiff-Francois syndrome, mandibulo-oculofacial syndrome, oculomandibulodyscephaly, oculomandibulofacial syndrome, progeria with cataract, progeria with microphthalmia.
(05 Mar 2000)
progestational 1. Favouring pregnancy; conducive to gestation; capable of stimulating the uterine changes essential for implantation and growth of a fertilised ovum.
2. Referring to progesterone, or to a drug with progesterone-like properties.
(05 Mar 2000)
progestational hormone <biochemistry, gynaecology> Produced in the corpus luteum, as an antagonist of oestrogens. Promotes proliferation of uterine mucosa and the implantation of the blastocyst, prevents further follicular development.
(18 Nov 1997)
progestational hormones A class of sex hormones associated with certain changes in the uterus and vagina during the menstrual cycle. They are necessary for the development of mammary tissue and for the maintenance of pregnancy.
(12 Dec 1998)
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