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proenzyme <biochemistry> A precursor of an enzyme that does not have full (or any) function until an inhibitory sequence has been removed.
This usually requires hydrolysis or limited {proteolysis of an inhibiting fragment that masks an active grouping) to render it active.
Examples include pepsinogen, trypsinogen, profibrolysin.
Synonym: zymogen.
(22 Sep 2002)
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