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prion protein (PrP) a 33?5 kD protein of uncertain function, in humans coded for by a gene on the short arm of chromosome 20. The 27?0 kD protease-resistant core is the functional, and perhaps only, component of prions; several isoforms have been identified and are responsible for prion disease. Extracellular prion protein aggregates into rod-shaped structures that resemble amyloid.
Ãâó: www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspz...
prion protein originally in its changed protease resistant form main ingredient of prions, which could be isolated from them. Later also used for the normal form - a protein found on the surface of various cells of animal origin and bound to the cell membrane.
Ãâó: www.schuett-abraham.de/glossar-en.htm
prion protein Protease-resistant membrane protein, also known as PrP: a normal host-coded protein that becomes protease-resistant in infected tissue
Ãâó: www.bseinquiry.gov.uk/report/volume6/glossary.htm
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