| mRNA | messenger Ribo-Nucleic Acid |
|---|---|
| H-mRNA | H-chain messenger ribonucleic acid |
| mRNA | messenger ribonucleic acid |
| pre-mRNA | precursor messenger ribonucleic acid |
| pre-mRNA | Precursor mRNA |
|---|---|
| mRNA | E-messenger RNA |
| mRNA | Messenger ribonucleic acid |
| NMD | Nonsense-mediated mRNA decay |
| mRNA | RNA |
| polygenic | <genetics> Pertaining to the combined action of alleles of more than one gene. Height is an example of a polygenic trait, as are predispositions to different types of heart disease. Origin: Gr. Gennan = to produce (14 Nov 1997) |
|---|---|
| polygenic diseases | Genetic disorders that are caused by the combined action of more than one gene. Examples of polygenic conditions include hypertension, coronary heart disease, diabetes, and peptic ulcers. Because such disorders depend on the simultaneous presence of several genes, they are not inherited as simply as single-gene diseases. (12 Dec 1998) |
| polygenic disorder | <genetics> Genetic disorders resulting from the combined action of alleles of more thanone gene (for example, heart disease, diabetes, and some cancers). Although such disorders are inherited, they depend on the simultaneous presence of several alleles, thus the hereditary patterns are usually more complex than those of single-gene disorders. (14 Oct 1997) |
| polygenic disorders | Genetic disorders resulting from the combined action of alleles of more than one gene (e.g., heart disease, diabetes, and some cancers). Although such disorders are inherited, they depend on the simultaneous presence of several alleles, thus the hereditary patterns are usually more complex than those of single- gene disorders. Compare single-gene disorders. (05 Mar 2000) |
| polygenic inheritance | Inheritance in which a measurable phenotype is generated by many loci, the contributions of which are statistically independent, additive, and of about equal value. (The latter are in accordance with the classical central limit therein and justify the use of the multivariate normal distribution in galtonian genetics). Synonym: polygenic inheritance. (05 Mar 2000) |
| diseases, polygenic | Genetic disorders that are caused by the combined action of more than one gene. Examples of polygenic conditions include hypertension, coronary heart disease, diabetes, and peptic ulcers. Because such disorders depend on the simultaneous presence of several genes, they are not inherited as simply as single-gene diseases. (12 Dec 1998) |
| alternative mRNA splicing | Splicing different exons in or out of messenger RNA to form different mRNA transcripts. (09 Oct 1997) |
| capping of mRNA | The process of adding a guanosine nucleotide to the 5'-end (the beginning) of an eukaryotic mRNA, then methylating (adding a -CH3 to) the guanosine. (09 Oct 1997) |
| maternal mRNA | <molecular biology> Messenger RNA found in oocytes and early embryos that is derived from the maternal genome during oogenesis. See: masked messenger RNA. (18 Nov 1997) |
| mRNA | <molecular biology> Single stranded RNA molecule that specifies the amino acid sequence of one or more polypeptide chains. This information is translated during protein synthesis when ribosomes bind to the mRNA. In prokaryotes, mRNA is normally formed by splicing a large primary transcript from a DNA sequence and protein synthesis starts while the mRNA is still being synthesised. Prokaryote mRNAs are usually very short lived (average t 1/2 is 5mins.). In contrast, in eukaryotes the primary transcripts (HnRNA) are synthesised in the nucleus and they are extensively processed to give the mRNA that is exported to the cytoplasm where protein synthesis takes place. This processing includes the addition of a 5' 5' linked 7 methyl guanylate cap at the 5' end and a sequence of adenylate groups at the 3' end, the poly A tail, as well as the removal of any introns and the splicing together of exons, only 10% of HnRNA leaves the nucleus. Eukaryote mRNAs are comparatively long lived with a half life ranging from 30minutes to 24 hours. (27 Jun 1999) |
| mRNA (2'-O-methyladenosine-N6-)-methyltransferase | <enzyme> Involved in capping mRNA Registry number: EC 2.1.1.62 Synonym: mRNA n(6)-adenosine methyltransferase, mra methyltransferase, RNA(2'-o-methyladenosine-n(6)-)methyltransferase (26 Jun 1999) |
| mRNA(adenine-N6)-methyltransferase | <enzyme> Methylates mRNA at internal adenosine within the consensus sequence puac(a/c/u) Registry number: EC 2.1.1.- Synonym: mRNA-a-n6-methyltransferase, mRNA(adenine-n6)-methylase (26 Jun 1999) |
| mRNA (guanine(N7))-methyltransferase | <enzyme> Catalyses s-adenosyl-l-methionine and g(5')pppr-RNA to yield s-adenosyl-l-homocysteine and m(7)g(5')pppr-RNA; mRNA containing an n(7)-methylguanine cap Registry number: EC 2.1.1.56 Synonym: mRNA (guanine-7-)methyltransferase, mRNA(guanine-7-)methyltransferase, RNA (guanine-7) methyltransferase, abd1 gene product (26 Jun 1999) |
| mRNA guanylyltransferase | <enzyme> Catalyses transfer of GMP residue from GTP to 5' end of RNA to form cap structure identified as g(5')pppn; can also modify synthetic poly(a) and poly(g) to form m7g(5')pppan and m7g(5')pppgn; see also capping enzyme, vaccinia virus Registry number: EC 2.7.7.50 Synonym: RNA guanylyltransferase, m-RNA guanylyltransferase, GTP mRNA guanylyltransferase, mRNA capping enzyme, mRNA 5'-guanylyltransferase, cgt1 gene product, ceg1 gene product (26 Jun 1999) |
| mRNA maturase | <enzyme> Also potent endonuclease involved in recombination Registry number: EC 2.7.7.- Synonym: RNA, mitochondrial maturase, RNA maturase (26 Jun 1999) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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