| 영문 | mutation | 한글 | 돌연변이 |
|---|---|---|---|
| 설명 | 세포의 dna 자체의 변이에 의해 일어나는 세포변이를 말한다. 이러한 경우 돌연변이로 일어난 세포는 그 이후 딸세포(daughter cell)에서도 그 변이가 여전히 유지되므로 종(species)의 변화나, 혹은 세포의 악성변환(malignant transformation)에 관여한다. |
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| ARMS | adverse reaction monitoring system; amplification refractory mutation system |
|---|---|
| MF | magnetic field; meat free; medium frequency; megafarad; membrane filler; merthiolate-formaldehyde [s... |
| TFM | testicular feminization male; testicular feminization mutation; total fluid movement; transmission e... |
| ARMS | Amplification Refractory Mutation System |
|---|---|
| MFD | Mutation frequency decline |
| RIP | Repeat Induced Point mutation |
| RSM | Restriction Site Mutation |
| SMART | Somatic Mutation And Recombination Test |
| cell polarity | 1. <cell biology> In epithelial cells the differentiation of apical and basal specialisations. In many epithelia the apical and baso lateral regions of plasma membrane differ in lipid and protein composition and are isolated from one another by tight junctions. The apical membrane may, for example: be the only region where secretory vesicles fuse or have a particular ionic pumping system. 2. A motile cell must have some internal polarity in order to move in one direction at a time: a region in which protrusion will occur (the front) must be defined. Locomotory polarity may be associated with the pericentriolar microtubule organising centre and can be perturbed by drugs that interfere with microtubule dynamics. (26 Mar 1998) |
|---|---|
| polarity | <physics> Literally having poles (like a magnet), but used to describe cells that have one or more axes of symmetry. <cell biology> In epithelial cells, the polarity meant is between apical and baso lateral regions, in moving cells, having a distinct front and rear. Some cells seem to show multiple axes of polarity (which will hinder forward movement). (18 Nov 1997) |
| polarity of translation | Decrease in the synthesis of proteins specified by genes distal to the operator and to the site of a nonsense, frameshift, deletion or insertion mutation in an operon. A mutation which produces polarity is called a polar mutation or a polarity mutation. (12 Dec 1998) |
| segment polarity gene | <molecular biology> A segmentation gene, responsible for specifying anterior posterior polarity within individual embryonic segments. In Drosophila, there are at least 10 such genes, for example gooseberry. (18 Nov 1997) |
| neuronal polarity | Distribution of specific functions to discrete cellular domains: for example axons and dendrites that have different molecular composition, morphology and ultrastructure and perform different functions. (18 Nov 1997) |
| egg polarity gene | A gene whose product distribution in the egg determines the anterior posterior axis of subsequent development. Best characterised in Drosophila: See: bicoid, maternal effect gene. (18 Nov 1997) |
| acquired mutation | A change in a gene or chromosome that occurs in a single cell after the conception of the individual. That change is then passed along to all cells descended from that cell. Acquired mutations are involved in the development of cancer. (12 Dec 1998) |
| addition-deletion mutation | <molecular biology> A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence. Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons. Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation. (21 Jun 2000) |
| addition mutation | <molecular biology> A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence. Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons. Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation. (21 Jun 2000) |
| amber mutation | <molecular biology> A mutation from a codon which codes for an amino acid into the amber codon UAG, which normally signals that the translation of mRNA into an amino acid chain should stop. The mutation causes the amino acid chain to stop forming before it is actually completed. (09 Oct 1997) |
| back mutation | <molecular biology> A mutation that causes a mutant gene to revert to its original wild-type base sequence. Compare: forward mutation. (09 Oct 1997) |
| reading-frameshift mutation | <molecular biology> A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence. Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons. Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation. (21 Jun 2000) |
| germinal mutation | A mutation in the germ cells (the cells which will undergo meiosis to form the gametes). Such mutations are therefore passed on to offspring. (09 Oct 1997) |
| germ-line mutation | Any detectable and heritable alteration in the lineage of germ cells. Mutations in these cells (i.e., "generative" cells ancestral to the gametes) are transmitted to progeny while those in somatic cells are not. (12 Dec 1998) |
| reverse mutation | <molecular biology> A mutation that causes a mutant gene to revert to its original wild-type base sequence. Compare: forward mutation. (09 Oct 1997) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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