| pol gene | <molecular biology> Genes coding for DNA polymerases of which there are three in E. Coli, polA, polB and polC coding for polymerases I, II and III respectively. Pol genes in oncogenic retroviruses code for reverse transcriptase. (18 Nov 1997) |
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| poland syndrome | <syndrome> A syndrome which is characterised by symbrachydactyly and aplasia of the sternal head of pectoralis major. (12 Dec 1998) |
| Poland's syndrome | <syndrome> An anomaly consisting of absence of the pectoralis major and minor muscles, ipsilateral breast hypoplasia, and absence of two to four rib segments. (05 Mar 2000) |
| polar | Describes a feature or phenomenon occuring at the end (pole) of an object (such as a planet) or organism (such as an amoeba). <chemistry> Describes a molecular that has a permanent electric dipole. See: polar group. Compare: nonpolar, nonpolar groups. (12 Mar 1998) |
| polar amino acid | An alpha-amino acid in which the functional group attached to the alpha-carbon (i.e., R in RCH(NH2)COOH) has hydrophilic properties; e.g., serine, cysteine, homocysteine. (05 Mar 2000) |
| polar anaemia | A form of anaemia sometimes observed in natives of temperate climates when they migrate to the Arctic or Antarctic regions. (05 Mar 2000) |
| polar body | <cell biology> In animals each meiotic division of the oocyte leads to the formation of one large cell (the egg) and a small polar body as the other cell. Polar body formation is a consequence of the very eccentric position of the nucleus and the spindle. (18 Nov 1997) |
| polar cataract | A capsular cataract limited to an area of the anterior or posterior pole of the lens. (05 Mar 2000) |
| polar cell | <cell biology> In animals each meiotic division of the oocyte leads to the formation of one large cell (the egg) and a small polar body as the other cell. Polar body formation is a consequence of the very eccentric position of the nucleus and the spindle. (18 Nov 1997) |
| polar compound | A compound in which the electric charge is not symmetrically distributed, so that there is a separation of charge or partial charge and formation of definite positive and negative poles; e.g., H2O. See also inorganic compound. (05 Mar 2000) |
| polar fibres | Those fibres of the mitotic spindle extending from the two poles of the spindle toward the equator. Compare: astral fibres, kinetochore fibres. (05 Mar 2000) |
| polar flagellation | <cell biology> Condition of having flagella attached at one end or both ends of the cell. (09 Oct 1997) |
| polar globule | <cell biology> In animals each meiotic division of the oocyte leads to the formation of one large cell (the egg) and a small polar body as the other cell. Polar body formation is a consequence of the very eccentric position of the nucleus and the spindle. (18 Nov 1997) |
| polar granule | <biology> Granules containing a basic protein found in insect eggs that induce the formation of and become incorporated into germ cells. (18 Nov 1997) |
| polar group | <chemistry> Any chemical grouping in which the distribution of electrons is uneven enabling it to take part in electrostatic interactions. (18 Nov 1997) |
| gene products, pol | Retroviral proteins coded by the pol gene. Often synthesised as a gag-pol fusion protein (fusion proteins, gag-pol) and later cleaved into final products that include reverse transcriptase, endonuclease/integrase, and viral protease. Pol is short for polymerase, the enzyme class of reverse transcriptase. (12 Dec 1998) |
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| genes, pol | DNA sequences that form the coding region for retroviral enzymes including reverse transcriptase, protease, and endonuclease/integrase. "pol" is short for polymerase, the enzyme class of reverse transcriptase. (12 Dec 1998) |
| fusion proteins, gag-pol | Polyprotein products of a fused portion of retroviral mRNA containing the gag and pol genes. The polyprotein is synthesised only five percent of the time since pol is out of frame with gag, and is generated by ribosomal frameshifting. (12 Dec 1998) |