platelet glycoprotein : KMLE 의학 검색 엔진 - 의학사전, 의학용어, 의학약어, 의학논문, 약품/의약품 검색

MeSH(Medical Subject Headings) 맞춤 검색 (http://www.nlm.nih.gov) 결과 : 2 페이지: 1

Platelet Glycoprotein GPIb-IX Complex - 새창 Platelet membrane glycoprotein complex essential for normal platelet adhesion and clot formation at sites of vascular injury. It is composed of three polypeptides, GPIb alpha, GPIb beta, and GPIX. Glycoprotein Ib functions as a receptor for von Willebrand factor and for thrombin. Congenital deficiency of the GPIb-IX complex results in Bernard-Soulier syndrome. The platelet glycoprotein GPV associates with GPIb-IX and is also absent in Bernard-Soulier syndrome.
Synonyms : CD42a Antigen, CD42b Antigen, CD42c Antigen, CD42d Antigen, Glycoprotein Ib, Glycoprotein Ib alpha, Glycoprotein Ib beta, Glycoprotein Ib-IX Complex, Platelet Glycoprotein IX, Antigen, CD42a, Antigen, CD42b, Antigen, CD42c, Antigen, CD42d
Platelet Glycoprotein GPIIb-IIIa Complex - 새창 Platelet membrane glycoprotein complex important for platelet adhesion and aggregation. It is an integrin complex containing INTEGRIN ALPHAIIB and INTEGRIN BETA3 which recognizes the arginine-glycine-aspartic acid (RGD) sequence present on several adhesive proteins. As such, it is a receptor for FIBRINOGEN; VON WILLEBRAND FACTOR; FIBRONECTIN; VITRONECTIN; and THROMBOSPONDINS. A deficiency of GPIIb-IIIa results in GLANZMANN THROMBASTHENIA.
Synonyms : Glycoproteins IIb-IIIa, Integrin alpha-IIb beta-3, GPIIb IIIa Receptors, Glycoproteins IIb IIIa, Integrin alpha IIb beta 3, Platelet Glycoprotein GPIIb IIIa Complex, Receptors, GPIIb-IIIa, alphaIIbbeta3, Integrin, beta-3, Integrin alpha-IIb