| pico | an extinct volcano in southern Mexico between Mexico City and Veracruz |
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| pico | a unit of capacitance equal to one trillionth of a farad |
| pico | a genus of Picidae |
| pico | a metric unit of length equal to one trillionth of a meter |
| pico | a metric unit of length equal to one trillionth of a meter |
| pico | a group of single-strand RNA viruses with a protein coat |
| pico | one trillionth of a second |
| pico | an edging of small loops, as on lace or ribbon |