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anemia <haematology> Too few red blood cells in the bloodstream, resulting in insufficient oxygen to tissues and organs.
Origin: Gr. Haima = blood
(16 Dec 1997)
melanotic neuroectodermal tumour of infancy A benign neoplasm of neuroectodermal origin that most often involves the anterior maxilla of infants in the first year of life. It presents clinically as a rapidly growing blue-black lesion producing a destructive radiolucency; histologically, it is characterised by small round undifferentiated tumour cells interspersed with larger polyhedral melanin-producing cells arranged in an alveolar configuration.
Synonym: melanoameloblastoma, pigmented ameloblastoma, pigmented epulis, progonoma of jaw, retinal anlage tumour.
(05 Mar 2000)
spongy degeneration of infancy Autosomal recessive degenerative disease of infancy; mostly in Jewish infants; onset typically within first 3-4 months of birth, consisting of blindness, psychomotor regression, enlarged head, optic atrophy, hypotonia, spasticity, increased N-acetylaspartic acid urinary excretion. MRI shows enlarged brain, decreased attenuation of cerebral and cerebellar white matter, and normal ventricles. Pathologically, there is increased brain volume and weight, and spongy degeneration in the subcortical white matter.
See: leukodystrophy.
Synonym: Canavan's sclerosis, Canavan-van Bogaert-Bertrand disease, spongy degeneration of infancy.
(05 Mar 2000)
diencephalic syndrome of infancy <paediatrics> Profound emaciation after initial normal growth, locomotor hyperactivity and euphoria, usually with skin pallor, hypotension and hypoglycaemia.
It is usually due to neoplasm involving the anterior hypothalamus.
(05 Mar 2000)
infancy Babyhood; the earliest period of extrauterine life; roughly, the first year of life.
(05 Mar 2000)
transient hypogammaglobulinaemia of infancy A type of primary immunodeficiency that occurs in infants of both sexes, usually before the sixth month of life, probably resulting from immaturity of lymphoid tissue.
Synonym: transient agammaglobulinaemia.
(05 Mar 2000)
fibrous hamartoma of infancy A tumour appearing usually in the upper arm or shoulder in the first two years of life and consisting of cellular fibrous tissue infiltrating the subcutis.
(05 Mar 2000)
calcification, physiologic Process by which organic tissue becomes hardened by the physiologic deposit of calcium salts.
(12 Dec 1998)
physiologic Normal, not pathologic, characteristic of or conforming to the normal functioning or state of the body or a tissue or organ, physiological.
(18 Nov 1997)
physiologic age Age estimated in terms of function.
(05 Mar 2000)
physiologic albuminuria Presence of slight traces of protein in otherwise normal urine.
Synonym: functional albuminuria.
(05 Mar 2000)
physiologic amenorrhoea Amenorrhoea of pregnancy or the menopause, not associated with an organic disorder.
(05 Mar 2000)
physiologic anaemia An obsolete term for apparent anaemia caused by increased fluid volume of the blood (overhydration).
(05 Mar 2000)
physiologic anisocoria A common (20% of normals) benign inequality of the pupils that may change from one hour to the next.
Synonym: essential anisocoria, physiologic anisocoria, simple-central anisocoria.
(05 Mar 2000)
physiologic antidote An agent that produces systemic effects contrary to those of a given poison.
(05 Mar 2000)
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