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physical dependence A condition in which the presence of a drug or alcohol is required to maintain normal functioning of the central nervous system. (See withdrawal symptoms.) Physical dependence is caused by changes in the relationships among nerve cell membranes, neurotransmitters and their receptors, and the reward pathway.
Ãâó: science.education.nih.gov/supplements/nih3/alcohol...
physical dependence State in which the use of a drug is required for a person to function normally. Such a state is revealed by withdrawing the drug and noting the occurrence of withdrawal symptoms. This state is relieved in time, or with readministration of the drug.
Ãâó: www.drugstrategy.central.sa.edu.au/20_druginfo/c_g...
physical dependence An adaptive physiological state that occurs with regular drug use and results in a withdrawal syndrome when drug use is stopped; usually occurs with tolerance. [3]
Ãâó: teens.drugabuse.gov/utilities/glossary2.asp
physical dependence The physical condition in which rapid discontinuation of a substance, such as alcohol, tobacco or a drug, causes a withdrawal reaction.
Ãâó: www.painconnection.org/MyTreatment/MayoClinic_glos...
physical dependence can be described as the occurrence of withdrawal syndromes after opioid use is stopped or quickly decreased without titration. Physical dependence can also occur if an antagonist is administered. This is not addiction. Physical dependence "??is not a clinical problem if patients are warned to avoid abrupt discontinuation of the drug, a tapering regimen is used (if treatment cessation is indicated), and opioid antagonist drugs (including agonist-antagonist analgesics) are avoided." 3
Ãâó: www1.va.gov/Pain_Management/page.cfm
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