| phorbol ester |
A polycyclic ester that is isolated from croton oil. The most common are phorbol-12-myristate-13-acetate (PMA) and 12-O-tetradecanoyl-phorbol-13-acetate (TPA). These are potent carcinogens or tumour promoters because they mimic diacylglycerol, and thereby irreversibly activate protein kinase C.
출처: www.nature.com/nrm/journal/v6/n1/glossary/nrm1548_...
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| phorbol |
a polycyclic alcohol occurring naturally in croton oil; it is the parent compound of the phorbol esters.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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