| pharmacophore |
The spatial orientation of various functional groups or features necessary for activity at a biomolecular target.
출처: www.nature.com/nrd/journal/v2/n5/glossary/nrd1086_...
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|---|---|
| pharmacophore |
The 3-D coordinates of atoms corresponding to pharmacologically active components of a drug molecule.
출처: www.genpromag.com/Glossary~LETTER~P.html
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| pharmacophore |
3D arrangement of atoms (or groups of atoms) responsible for the pharmacological activity of a drug.
출처: www.chemsoc.org/exemplarchem/entries/2003/nottingh...
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| pharmacophore |
A pharmacophore is the ensemble of steric and electronic features that is necessary to ensure the optimal supramolecular interactions with a specific biological target structure and to trigger (or to block) its biological response. A pharmacophore does not represent a real molecule or a real association of functional groups, but a purely abstract concept that accounts for the common molecular interaction capacities of a group of compounds towards their target structure.
출처: www.exchemistry.com/glossary.html
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| pharmacophore |
The particular group or arrangement of atoms in a molecule that gives the material its medicinal activity.
출처:
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