| peptidyltransferase | <enzyme> An enzyme that catalyses the transfer of aminoacyl-trna to formyl-methionine-trna or peptidyl-trna during peptide chain elongation. It is a part of the 50 s (bacteria) and 60 s (eukaryotes) ribosomal subunits. Integral enzymic activity of the large subunit of a ribosome, catalysing the formation of a peptide bond between the carboxy terminus of the nascent chain and the amino group of an arriving tRNA associated amino acid. Chemical name: Peptidyl-tRNA:aminoacyl-tRNA N-peptidyltransferase Registry number: EC 2.3.2.12 (12 Dec 1998) |
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