| paroxysmal cold haemoglobinuria | <haematology> A rare blood disorder caused by antibodies which destroy red blood cells upon exposure to the cold. The antibodies are formed against a specific blood group and are triggered by the cold. The cause is unknown but the disease has been associated with syphilis and some viral infections. Serum haemoglobin and urine haemoglobin are increased during the attacks. The disease is chronic and treatment is difficult. Some cases resolve spontaneously without treatment. Origin: Gr. Ouron = urine (27 Sep 1997) |
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| paroxysmal nocturnal haemoglobinuria | An infrequent disorder with insidious onset (usually in the third or fourth decade) and chronic course, characterised by episodes of haemolytic anaemia, haemoglobinuria (chiefly at night), pallor, icterus or bronzing of the skin, a moderate degree of splenomegaly, and sometimes hepatomegaly; red blood cells are usually macrocytic and vary considerably in size, but there is no evidence of spherocytosis, erythrophagocytosis, or abnormal leukocytes. The disorder is a result of an abnormality of the red cell membrane which makes the red cell unusually sensitive to lysis by complement. Synonym: Marchiafava-Micheli anaemia, Marchiafava-Micheli syndrome. (05 Mar 2000) |
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| haemoglobinuria, paroxysmal | Disorder characterised by intravascular haemolysis and haemoglobinuria. Some cases occur on exposure to cold and are due to the presence of an autohemolysin in the serum. Other cases are more marked during or immediately after sleep and are considered to be due to an acquired intracorpuscular defect. (12 Dec 1998) |
| bacillary haemoglobinuria | An acute toxaemic disease of cattle caused by the bacterium Clostridium haemolyticum and characterised by severe depression, fever, abdominal pain, dyspnea, dysentery, haemoglobinuria, and rapid death; also occurs in sheep and, rarely, in dogs. (05 Mar 2000) |
| bovine haemoglobinuria | An infectious disease of cattle caused by Babesia species and transmitted by ticks. Synonym: bovine haemoglobinuria, redwater fever, Texas fever, tick fever. (05 Mar 2000) |
| malarial haemoglobinuria | A condition, now uncommon, resulting from Plasmodium falciparum infection (malignant tertian malaria with severe haemolysis); frequently seen in Caucasians after interrupted treatment with quinine. Synonym: blackwater fever, haemoglobinuric fever, West African fever. (05 Mar 2000) |
| march haemoglobinuria | A form occurring after marathon races, protracted marching, or heavy physical exercise. (05 Mar 2000) |
| postparturient haemoglobinuria | <haematology, obstetrics> A sudden, severe haemolytic disease that appears sporadically in well nourished dairy cows 2 to 4 weeks after calving, and usually occurs in stabled animals in the winter and early spring; the cause is not known, although the disease is often associated with hypophosphatemia. Synonym: puerperal haemoglobinaemia, puerperal haemoglobinuria. (05 Mar 2000) |
| haemoglobinuria | Haemoglobin in the urine. (12 Dec 1998) |
| puerperal haemoglobinuria | <haematology, obstetrics> A sudden, severe haemolytic disease that appears sporadically in well nourished dairy cows 2 to 4 weeks after calving, and usually occurs in stabled animals in the winter and early spring; the cause is not known, although the disease is often associated with hypophosphatemia. Synonym: puerperal haemoglobinaemia, puerperal haemoglobinuria. (05 Mar 2000) |
| intermittent haemoglobinuria | <nephrology> Recurrent episodic attacks of haemoglobinuria characteristic of paroxysmal nocturnal haemoglobinuria or paroxysmal cold haemoglobinuria. (05 Mar 2000) |
| toxic haemoglobinuria | Haemoglobinuria occurring after the ingestion of various poisons, in certain blood diseases, and in certain infections. (05 Mar 2000) |
| epidemic haemoglobinuria | The presence of haemoglobin, or of pigments derived from it, in the urine of young infants, attended with cyanosis, jaundice, and other conditions; may be due to secondary methemoglobinaemia; also called Winckel's disease. (05 Mar 2000) |
| benign paroxysmal peritonitis | familial paroxysmal polyserositis |
| benign paroxysmal postural vertigo | A recurrent, brief form of postural vertigo occurring in clusters; believed to result from displaced remnants of utricular otoconia. Synonym: cupulolithiasis. (05 Mar 2000) |
| paroxysmal | <cardiology, neurology> Recurring in paroxysms, spasms or seizures. (18 Nov 1997) |