| paraneoplastic | Relating to or characteristic of paraneoplasia. (05 Mar 2000) |
|---|---|
| paraneoplastic acrokeratosis | <syndrome> Erythematous to plum-coloured scaly acral skin lesions, paronychia, and nail dysplasia; associated with cancer of the upper respiratory or upper alimentary tract. Synonym: paraneoplastic acrokeratosis. (05 Mar 2000) |
| paraneoplastic encephalomyelopathy | An encephalomyelopathy as a remote effect of carcinoma, most often oat cell carcinoma of the lung; characterised by extensive nerve cell loss, which may be diffuse, but often predominates in particular portions of the central nervous system, particularly the limbic lobes, medulla, cerebellum, and gray matter of the spinal cord. Synonym: carcinomatous encephalomyelopathy, encephalomyelitis associated with carcinoma, paracarcinomatous encephalomyelopathy. (05 Mar 2000) |
| paraneoplastic syndrome | <oncology, syndrome> A collection of symptoms or clinical signs that are found in patients that have malignant disease. By definition, the signs and symptoms are not produced by a direct effect of a tumour or its metastasis nor due to direct invasion, compression, metastasis, infection, nutritional deficiency or treatment of the underlying neoplasm. Paraneoplastic syndromes can arise from tumour produced biologically active polypeptides or proteins, autoimmunity or immune complex production and immune suppression, blockade of the normal effect of a hormone, the release of substances from tumour associated endothelium which are not normally released and finally unknown causes. The best characterised paraneoplastic syndrome is the syndrome of inappropriate ADH. (15 Dec 1997) |
| paraneoplastic syndromes | In patients with neoplastic diseases a wide variety of clinical pictures which are indirect and usually remote effects produced by tumour cell metabolites or other products. (12 Dec 1998) |