| paramagnetic | Magnetic, as opposed to diamagnetic. A paramagnetic substance. Paramagnet"ically. Origin: Pref. Para- + magnetic. Source: Websters Dictionary (01 Mar 1998) |
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| electron paramagnetic resonance | <physics> A spectrometric method, based on measurement of electron spins and magnetic moments, for detecting and estimating free radicals in reactions and in biological systems. Synonym: electron paramagnetic resonance. (05 Mar 2000) |
| BRCA1 breast cancer susceptibility gene | This mutated (changed) version of the BRCA1 gene makes a person susceptible to developing breast cancer. (12 Dec 1998) |
| breast cancer susceptibility genes | Inherited factors that predispose to breast cancer. Put otherwise, these genes make one more susceptible to the disease and so increase the risk of developing breast cancer. Two of these genes, BRCA1 and BRCA2, have been identified (and prominently publicised). Several other genes (those for the Li-Fraumeni syndrome, Cowden disease, Muir-Torre syndrome, and ataxia-telangiectasia) are also known to predispose to breast cancer. However, since all of these known breast cancer susceptibility genes together do not account for more than a minor fraction (1/5th at most) of breast cancer that clusters in families, it is clear that more breast cancer genes remain to be discovered. (12 Dec 1998) |
| cancer, breast, susceptibility genes | Inherited factors that predispose to breast cancer. Put otherwise, these genes make one more susceptible to the disease and so increase the risk of developing breast cancer. Two of these genes, BRCA1 and BRCA2, have been identified (and prominently publicised). Several other genes (those for the Li-Fraumeni syndrome, Cowden disease, Muir-Torre syndrome, and ataxia-telangiectasia) are also known to predispose to breast cancer. However, since all of these known breast cancer susceptibility genes together do not account for more than a minor fraction (1/5th at most) of breast cancer that clusters in families, it is clear that more breast cancer genes remain to be discovered. (12 Dec 1998) |
| cancer susceptibility gene | tumour suppressor gene |
| genes, breast cancer susceptibility | Inherited factors that predispose to breast cancer. Put otherwise, these genes make one more susceptible to the disease and so increase the risk of developing breast cancer. Two of these genes, BRCA1 and BRCA2, have been identified (and prominently publicised). Several other genes (those for the Li-Fraumeni syndrome, Cowden disease, Muir-Torre syndrome, and ataxia-telangiectasia) are also known to predispose to breast cancer. Howeverm, since all of these known breast cancer susceptibility genes together do not account for more than a minor fraction (1/5th at most) of breast cancer that clusters in families, it is clear that more breast cancer genes remain to be discovered. See related entries to: BRCA1; BRCA2; Breast cancer, familial. (12 Dec 1998) |
| colourimetric caries susceptibility test | A colourimetric test for determining dental caries activity or susceptibility based on the rate of acid production by acidogenic oral microorganisms (e.g., lactobacillus) in a glucose medium, using bromcresol green as the indicator, and producing a colour change from green to yellow. Synonym: colourimetric caries susceptibility test. (05 Mar 2000) |
| susceptibility | Origin: Cf. F. Susceptibilite. 1. The state or quality of being susceptible; the capability of receiving impressions, or of being affected. 2. Specifically, capacity for deep feeling or emotional excitement; sensibility, in its broadest acceptation; impressibility; sensitiveness. <physics> Magnetic susceptibility, the intensity of magnetization of a body placed in a uniform megnetic field of unit strength. Synonym: Capability, sensibility, feeling, emotion. Source: Websters Dictionary (01 Mar 1998) |
| susceptibility testing | The determination of the ability of an antibiotic to kill or inhibit the growth of bacteria. (05 Mar 2000) |
| disease susceptibility | A constitution or condition of the body which makes the tissues react in special ways to certain extrinsic stimuli and thus tends to make the individual more than usually susceptible to certain diseases. (12 Dec 1998) |
| abscopal effect | A reaction produced following irradiation but occurring outside the zone of actual radiation absorption. (05 Mar 2000) |
| additive effect | <biochemistry, chemistry> An additive effect is the overall biological effect two chemicals acting together and which is the simple sum of the effects of the chemicals acting independently. Compare: antagonism. (15 Jan 1998) |
| adverse effect | This is an abnormal or harmful effect to an organism caused by exposure to a chemical. It is indicated by some result such as death, a change in food or water consumption, altered body and organ weights, altered enzyme levels, or visible illness. An effect may be classed as adverse if it causes functional or anatomical damage, causes irreversible change in the homeostasis of the organism, or increases the susceptibility of the organism to other chemical or biological stress. A non-adverse effect will usually be reversed when the organism is no longer being exposed to the chemical. (09 Oct 1997) |
| Anrep effect | A small transient positive inotropic effect of abrupt increases of systolic aortic and left ventricular pressures related to recovery from transient subendocardial ischemia (e.g., cold pressor test). (05 Mar 2000) |