| tumor | 1. <oncology> An abnormal mass of tissue that results from excessive cell division that is uncontrolled and progressive, also called a neoplasm. Tumours perform no useful body function. They may be either benign (not cancerous) or malignant. 2. Swelling, one of the cardinal signs of inflammations, morbid enlargement. Origin: L. Tumere = to swell (12 May 1997) |
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| tumor marker | <investigation, oncology> A substance in the body that usually indicates the presence of cancer. These markers are usually specific to certain types of cancer and are usually found in the blood or other tissue samples. Examples are alphafetoprotein (AFP), human chorionic gonadotropin, and lactate dehydrogenase (LDH). They may be indicators of tumour stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids. (18 Jul 2002) |
| tumor necrosis factor | <cytokine> Originally described as a tumour inhibiting factor in the blood of animals exposed to bacterial lipopolysaccharide or Bacille Calmette-Guerin. Preferentially kills tumour cells in vivo and in vitro, causes necrosis of certain transplanted tumours in mice and inhibits experimental metastases. Human Tumour Necrosis factor alpha is a protein of 157 amino acids and has a wide range of pro inflammatory actions. Usually considered a cytokine. Synonym: cachectin. Acronym: TNF (13 Nov 1997) |
| adenocarcinoma, papillary | An adenocarcinoma containing finger-like processes of vascular connective tissue covered by neoplastic epithelium, projecting into cysts or the cavity of glands or follicles. It occurs most frequently in the ovary and thyroid gland. (12 Dec 1998) |
| carcinoma, papillary | A malignant neoplasm characterised by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. (12 Dec 1998) |
| carcinoma, papillary, follicular | A thyroid neoplasm of mixed papillary and follicular arrangement. Its biological behaviour and prognosis is the same as that of a papillary adenocarcinoma of the thyroid. (12 Dec 1998) |
| papillary | <anatomy> Pertaining to or resembling papilla or nipple. (18 Nov 1997) |
| papillary adenocarcinoma | <tumour> An adenocarcinoma containing finger-like processes of vascular connective tissue covered by neoplastic epithelium, projecting into cysts or the cavity of glands or follicles; occurs most frequently in the ovary and thyroid gland. (05 Mar 2000) |
| papillary adenoma of large intestine | <tumour> Appears as a solitary sessile, often large, tumour of colonic mucosa composed of mucinous epithelium covering delicate vascular projections; malignant change occurs frequently; hypersecretion occurs rarely. Also known as adenoma. Synonym: papillary adenoma of large intestine. (05 Mar 2000) |
| papillary carcinoma | <tumour> A malignant neoplasm characterised by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. (05 Mar 2000) |
| papillary cystadenoma lymphomatosum | <oncology, tumour> A benign tumour characterised histologically by tall columnar epithelium within a lymphoid tissue stroma. It is usually found in the salivary glands, especially the parotid. (25 Jun 1999) |
| papillary cystic adenoma | <tumour> An adenoma in which the lumens of the acini are frequently distended by fluid, and the neoplastic epithelial elements tend to form irregular, fingerlike projections. (05 Mar 2000) |
| papillary ducts | The largest straight excretory duct's in the kidney medulla and papillae whose openings form the area cribrosa; they are a continuation of the collecting tubules. Synonym: Bellini's ducts. (05 Mar 2000) |
| papillary foramina of kidney | Numerous minute openings, the apertures of the papillary ducts converging on the apical pole of each renal papilla. Synonym: foramina papillaria renis. (05 Mar 2000) |
| papillary hidradenoma | <tumour> A solitary benign tumour occurring in women usually in the labia majora, cystic and papillary, and composed of epithelium resembling that of apocrine glands. Synonym: apocrine adenoma, hidradenoma papilliferum. (05 Mar 2000) |