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P-A conduction time See: atrioventricular conduction.
(05 Mar 2000)
P-A interval The time from onset of the P wave to the initial rapid deflection of the A wave in the His bundle electrogram (normally 25-45 msec); it represents the intra-atrial conduction time.
(05 Mar 2000)
p-aminoazobenzene <chemical> Used in the form of its salts as a dye and as an intermediate in manufacture of acid yellow, diazo dyes, and indulines.
Pharmacological action: dyes.
Chemical name: Benzenamine, 4-(phenylazo)-
(12 Dec 1998)
p-aminobenzoic acid A factor in the vitamin B complex, a part of all folic acids and required for its formation; neutralises the bacteriostatic effects of the sulfonamides since it furnishes an essential growth factor for bacteria, the utilization with which the sulfonamides interfere; used as an ultraviolet screen in lotions and creams.
Synonym: paraaminobenzoic acid, vitamin Bx.
Acronym: PABA
(05 Mar 2000)
p-aminohippurate clearance A good measure of renal plasma flow, which it slightly underestimates; when a low plasma concentration of p-aminohippurate (PAH) is maintained by intravenous infusion, the kidney extracts and excretes almost all of the PAH from the plasma before it reaches the renal vein.
(05 Mar 2000)
p-aminohippuric acid <chemical> N-(4-aminobenzoyl)glycine. A diagnostic aid used as the sodium salt in renal function tests.
Chemical name: Glycine, N-(4-aminobenzoyl)-
(12 Dec 1998)
p-aminohippuric acid synthase <enzyme> An enzyme in the liver that catalyses the synthesis of p-aminohippuric acid from p-aminobenzoic acid (or the CoA-derivative) and glycine. It may be identical with glycine acyltransferase.
Acronym: PAH
(05 Mar 2000)
p-aminopropiophenone <drug> An antidote for cyanide poisoning.
Chemical name: 1-(4-Aminophenyl)-1-propanone
Acronym: PAPP
(21 Jun 2000)
p-aminosalicylic acid <chemical> 4-amino-2-hydroxybenzoic acid. An antitubercular agent often administered in association with isoniazid. The sodium salt of the drug is better tolerated than the free acid.
Pharmacological action: antitubercular agents.
Chemical name: Benzoic acid, 4-amino-2-hydroxy-
(12 Dec 1998)
p-azobenzenearsonate <chemical> 4,4'-azodibenzenearsonic acid. A hapten capable of eliciting both antibody formation and delayed hypersensitivity when bound to aromatic amino acids, polypeptides or proteins. It is used as an immunologic research tool.
Chemical name: Arsonic acid, (azodi-4,1-phenylene)bis-
(12 Dec 1998)
p-chloral A polymer of chloral obtained by prolonged contact with sulfuric acid; it has properties similar to those of chloral hydrate.
Synonym: metachloral, p-chloral, trichloral.
(05 Mar 2000)
p-chloroamphetamine <chemical> Chlorinated analog of amphetamine. Potent neurotoxin that causes release and eventually depletion of serotonin in the CNS. It is used as a research tool.
Pharmacological action: serotonin agents.
Chemical name: Benzeneethanamine, 4-chloro-alpha-methyl-
(12 Dec 1998)
p-chloromercuribenzoate Organic mercury compound (ClHgC6H4COO-, ClHgBzO-) that reacts with -SH groups of proteins; an inhibitor of action of those proteins (enzymes) that depend on -SH reactivity.
See: p-mercuribenzoate.
Acronym: PCMB
(05 Mar 2000)
p-chlorophenol A disinfectant effective against most Gram-negative organisms; also available as camphorated parachlorophenol.
Synonym: p-chlorophenol.
(05 Mar 2000)
P-congenitale The P-wave pattern in the electrocardiogram seen in some cases of congenital heart disease, consisting of tall peaked P waves in leads I, II, aVF, and aVL (usually largest in lead II) with predominant positivity of diphasic waves in V1-2.
See: spannungs-P.
(05 Mar 2000)
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