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oxo- <prefix> Prefix denoting addition of oxygen; used in place of keto-in systematic nomenclature.
See: hydroxy-, oxa-, oxy-.
(05 Mar 2000)
oxo-acid-lyases <enzyme> Enzymes that catalyze the cleavage of a carbon-carbon bond of a 3-hydroxy acid.
Registry number: EC 4.1.3.
(12 Dec 1998)
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asparagine-oxo-acid aminotransferase <enzyme> Consider also EC 2.6.1.45, serine-glyoxylate aminotransferase, which also acts on asparagine
Registry number: EC 2.6.1.14
Synonym: asparagine transaminase
(26 Jun 1999)
ornithine-oxo-acid transaminase <enzyme> A pyridoxal phosphate enzyme that catalyses the formation of glutamate gamma-saemialdehyde and an l-amino acid from l-ornithine and a 2-keto-acid.
Chemical name: L-Ornithine:2-oxo-acid aminotransferase
Registry number: EC 2.6.1.13
(12 Dec 1998)
oxo acid An acid containing a ketone group (-CO-) in addition to the acid group(s); alpha-keto acid refers to a 2-oxo acid (e.g., pyruvic acid); beta-keto acid refers to a 3-oxo acid (e.g., acetoacetic acid), etc.
Synonym: oxo acid.
Alpha-keto acid dehydrogenase, one of several distinct multienzyme complexes that catalyses the formation of an acyl-CoA derivative, CO2, and NADH from an alpha-keto acid, NAD+, and coenzyme A; maple syrup urine disease results from several different inherited defects in the mitochondrial branched chain alpha-keto acid dehydrogenase complex.
(05 Mar 2000)
2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate decarboxylase <enzyme> Catalyses conversion of 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate to 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate; enzyme d of p-cumate catabolic pathway in pseudomonas putida
Registry number: EC 4.1.1.-
Synonym: cmtd gene product
(26 Jun 1999)
2-hydroxy-6-oxo-2,4-heptadienoate hydrolase <enzyme> Above cpd hydrolyzed to 2-oxopent-4-enoate (2-hydroxypenta-2,4-dienoate); enzyme e of p-cumate catabolic pathway in pseudomonas putida
Registry number: EC 3.7.-
Synonym: hodh hydrolase, 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase, cmte gene product
(26 Jun 1999)
2-oxo-1,2-dihydroquinoline 5,6-dioxygenase <enzyme> An aromatic ring dioxygenase; catalyses the conversion of 2-oxo-1,2-dihydroquinoline to 5,6-dihydro-5,6-dihydroxy-2-oxo-1,2-dihydroquinoline; mw 260 kD
Registry number: EC 1.14.12.-
Synonym: 2-oxo-1,2-dihydroquinoline NADH - oxygen 5,6-oxidoreductase (5,6-hydroxylating), odhq dioxygenase
(26 Jun 1999)
2-oxo-1,2-dihydroquinoline 8-monooxygenase <enzyme> A 2-component enzyme from pseudomonas putida: a monomeric iron-sulfur flavoprotein containing fad and plant-type ferredoxin (mr 38,000) which transfers electrons from NADH to the oxygenase (mr 330,000), also an iron-sulfur protein with 6 identical subunits
Registry number: EC 1.14.13.-
Synonym: 2-oxo-1,2-dihydroquinoline 8-hydroxylase, 2-oxo-1,2-d 8-hydroxylase, 2-oxo-1,2-dihydroquinoline, NADH - oxygen oxidoreductase (8-hydroxylating)
(26 Jun 1999)
2-oxo-5-guanidovaleric acid The deaminated derivative of arginine.
(05 Mar 2000)
2-oxo-delta(3)-4,5,5--trimethylcyclopentenyl acetyl-CoA monooxygenase <enzyme> Nadph-dependent baeyer-villiger monooxygenase that catalyses conversion of 2-(2'-acetoxyethyl)cyclohexanone to 7-(2'-acetoxyethyl)-2-oxepanone
Registry number: EC 1.14.13.-
Synonym: odtac monooxygenase
(26 Jun 1999)
2-oxo-delta-(3)-4,5,5-trimethylcyclopentenylacetyl-CoA oxygenase <enzyme> Specific for NADPH as electron donor; incorporates single molecule of oxygen
Registry number: EC 1.14.13.-
Synonym: otmcpa CoA oxygenase, 2-oxo-delta-(3)-4,5,5-trimethylcyclopentenylacetyl-coenzyme a oxygenase
(26 Jun 1999)
3-oxo-5 beta-steroid delta 4-dehydrogenase <enzyme> Do not confuse with EC 1.3.1.23 (cholestenone 5 beta-reductase) which is also steroid 5 beta-reductase in chemline; do not use for enzyme using NADP-see EC 1.3.1.23 and EC 1.3.1.3
Chemical name: 3-oxo-5 beta-steroid delta(4)dehydrogenase
Registry number: EC 1.3.99.6
Synonym: steroid 5 beta-reductase, testosterone 5 beta-reductase, 4-ene-5 beta-reductase, delta(4)-3-ketosteroid-5 beta-(acceptor)-reductase, testosterone 5beta-reductase, delta(4)-5beta-reductase, cytosolic 4-ene-reductase
(26 Jun 1999)
4-oxo-5-hydroxyvalerate dehydrogenase <enzyme> Uses nad or nadp; involved in transamination route of porphyrin biosynthesis
Registry number: EC 1.1.1.-
Synonym: 4-ox-5-hy dehydrogenase
(26 Jun 1999)
6-pyruvoyl tetrahydropterin (2'-oxo)reductase <enzyme> From rat brain; catalyses the reduction of 6-pyruvoyl tetrahydropterin in the presence of NADPH to 6-(2'-hydroxy-1'-oxopropyl-5,6,7,8-tetrahydropterin); will only catalyze the reduction of the c-2'-oxo group
Registry number: EC 1.2.1.-
Synonym: 6pph4 reductase
(26 Jun 1999)
8-oxo-dGMPase <enzyme> Degrades 8-oxo-7,8-dihydro-2'-deoxyguanosine-5'-monophosphate to 8-oxo-7,8-dihydro-2'-deoxyguanosine
Registry number: EC 3.1.3.-
(26 Jun 1999)
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