| osteolysis | <pathology> The dissolution of bone, applied especially to the removal or loss of the calcium of bone. Origin: Gr. Lysis = dissolution (18 Nov 1997) |
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| osteolysis, essential | Syndromes of bone destruction where the cause is not obvious such as neoplasia, infection, or trauma. The destruction follows various patterns: massive (gorham disease), multicentric (hajdu-cheney syndrome, winchester syndrome), or carpal/tarsal. (12 Dec 1998) |
| acro-osteolysis | <radiology> Loss of terminal tufts of digits, scleroderma / connective-tissue disease, psoriatic arthritis, Reiter disease, frostbite (thumbs spared), leprosy, polyvinylchloride exposure, hyperparathyroidism, Lesch-Nyhan syndrome (they bite them off), cleidocranial dysostosis, progeria, pyknodysostosis (aplasia/hypoplasia of distal digits), (?) sarcoidosis (12 Dec 1998) |
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| spontaneous osteolysis | <radiology> Several syndromes of vanishing bones: (Cf: rapid demineralization), idiopathic hereditary osteolysis, autosomal dominant, manifest in early childhood, carpals and tarsals involved first, autosomal-recessive carpal and tarsal osteolysis, idiopathic osteolysis with nephropathy, carpals, tarsals, adjacent tubular bones involved, azotaemia may lead to death in early adulthood, massive osteolysis of Gorham, angiomatous destruction (12 Dec 1998) |