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| ¿µ¹® | osmotic pressure | ÇÑ±Û | »ïÅõ¾Ð |
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| OF | occipitofrontal; open field [test]; optical fundus; orbitofrontal; osmotic fragility; osteitis fibro... |
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| COP | capillary osmotic pressure; change of plaster; coefficient of performance; colloid oncotic pressure;... |
| HCF | [fetal] head-to-cervix force; heparin cofactor; hereditary capillary fragility; highest common facto... |
| MCF | macrophage chemotactic factor; median cleft face; medium corpuscular fragility; microcomplement fixa... |
| VFS | vascular fragility syndrome |
| COP | Colloid osmotic pressure |
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| HOST | Hypo-osmotic swelling test |
| HOS | hypo-osmotic swelling test |
| osmotic fragility | The susceptibility, or lack of resistance, of erythrocytes to haemolysis when exposed to increasingly hypotonic saline solutions. (12 Dec 1998) |
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| capillary fragility | The lack of resistance, or susceptibility, of capillaries to damage or disruption under conditions of increased stress. (12 Dec 1998) |
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| capillary fragility test | A tourniquet test used to determine presence of vitamin C deficiency or thrombocytopenia; a circle 2.5 cm in diameter, the upper edge of which is 4 cm below the crease of the elbow, is drawn on the inner aspect of the forearm, pressure midway between the systolic and diastolic blood pressure is applied above the elbow for 15 minutes, and a count of petechiae within the circle is made: 10, normal; 10 to 20, marginal zone; over 20, abnormal. See: Rumpel-Leede test. Synonym: capillary resistance test, vitamin C test. (05 Mar 2000) |
| fragility | Brittleness; liability to break, burst, or disintegrate. Synonym: fragilitas. Origin: L. Fragilitas (05 Mar 2000) |
| fragility of the blood | The susceptibility, or lack of resistance, of erythrocytes to haemolysis when exposed to increasingly hypotonic saline solutions. (12 Dec 1998) |
| fragility test | A test that measures the resistance of erythrocytes to haemolysis in hypotonic saline solutions; erythrocytes to be tested are added to varying concentrations of saline (usually ranging from 0.85 to 0.10% sodium chloride with 0.05% increments), and beginning and complete haemolysis are measured; normal erythrocytes show initial haemolysis at concentrations of 0.45 to 0.39% and complete haemolysis at 0.33 to 0.30%; in hereditary spherocytosis the fragility of the erythrocytes is markedly increased, whereas in thalassaemia, sickle cell anaemia, and obstructive jaundice the fragility of the erythrocytes is usually reduced. Synonym: erythrocyte fragility test. (05 Mar 2000) |
| diuretics, osmotic | Diuretics that are filtered at the glomerulus and reabsorbed in the renal tubule only to a limited extent. They thus increase the amount of osmotically active solute in the urine and a corresponding increase in urine volume. These compounds also increase the osmolality of plasma, thereby increasing the diffusion of water from the intraocular and cerebrospinal fluids; they can be used for reducing the pressure and volume of these fluids. (12 Dec 1998) |
| iso-osmotic | <physiology> Having the same total osmotic pressure or osmolality as another fluid (ordinarily intracellular fluid); such a fluid is not isosmotic if it includes solutes that freely permeate cell membranes. Synonym: iso-osmotic. (05 Mar 2000) |
| osmotic | <chemistry> Pertaining to or of the nature of osmosis (= the passage of pure solvent from a solution of lesser to one of greater solute concentration when the two solutions are separated by a membrane which selectively prevents the passage of solute molecules, but is permeable to the solvent). (18 Nov 1997) |
| osmotic diuresis | Diuresis due to a high concentration of osmotically active substances in the renal tubules (e.g., urea, sodium sulfate), which limit the reabsorption of water. (05 Mar 2000) |
| osmotic diuretics | Drugs, such as mannitol, which by their osmotic effects retain water during urine formation and thus dilute electrolytes in the urine, making resorption less efficient; they promote the elimination of water and electrolytes in the urine. (05 Mar 2000) |
| osmotic nephrosis | Swelling of renal tubular epithelium associated with glomerular filtration of sugars and dextrose; the swelling is due to formation of cytoplasmic vesicles by pinocytosis, and is reversible, probably with no dysfunction, when produced by glucose or mannitol. (05 Mar 2000) |
| osmotic pressure | See: osmosis. The pressure required to prevent osmotic flow across a semi permeable membrane separating two solutions of different solute concentration. Equal to the pressure that can be set up by osmotic flow in this system. (18 Nov 1997) |
| osmotic shock | Passage of solvent into a membrane bound structure due to osmosis, causing rupture of the membrane. A method of lysing cells or organelles. (18 Nov 1997) |
| effective osmotic pressure | That part of the total osmotic pressure of a solution that governs the tendency of its solvent to pass across a boundary, usually a semipermeable membrane; it is commonly represented by the product of the total osmotic pressure of the solution and the ratio (corrected for activities) of the number of dissolved particles that do not permeate the bounding membrane to the total number of particles in the solution; equivalent in meaning to tonicity; commonly expressed in equivalent units of osmolality rather than pressure per se. (05 Mar 2000) |
Synonyms : Fragility, Osmotic, Fragility, Saline
| osmotic fragility |
susceptibility of erythrocytes to rupture when subjected to increasingly hypotonic saline solutions; seen in some forms of hemolytic anemia and spherocytosis. See also osmotic fragility test, under test.
Ãâó: www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspz...
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| osmotic fragility t. |
(for spherocytosis): heparinized or defibrinated blood is placed in tubes of sodium chloride solution (pH 7.4) varying in concentration from 0.85 to 0.00 per cent (w/v); the amount of hemolysis in each tube is determined colorimetrically. Increased fragility indicates spherocytosis.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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