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oncofetal antigen An antigen normally expressed in the fetus that may reappear in the adult in association with certain tumors. Examples include alpha-fetoprotein and carcinoembryonic antigens.
Ãâó:
oncofetal protein A cell surface marker, such as carcinoembryonic antigen or alpha-fetoprotein, that is expressed on some malignant cells. The detection of such proteins may be used to monitor the clinical course of some cancers (e.g., cancer of
Ãâó:
oncofetal occurring both in tumor tissue and during fetal development; see under antigen.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
oncofetal a. an antigenic gene product that is expressed during fetal development, partially or completely repressed in adult tissues, and derepressed in some tissues that have undergone neoplastic transformation; oncofetal antigens, e.g., alpha-fetoprotein, carcinoembryonic antigen, and pancreatic oncofetal antigen, are thus useful tumor markers.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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