| tumor | 1. <oncology> An abnormal mass of tissue that results from excessive cell division that is uncontrolled and progressive, also called a neoplasm. Tumours perform no useful body function. They may be either benign (not cancerous) or malignant. 2. Swelling, one of the cardinal signs of inflammations, morbid enlargement. Origin: L. Tumere = to swell (12 May 1997) |
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| tumor marker | <investigation, oncology> A substance in the body that usually indicates the presence of cancer. These markers are usually specific to certain types of cancer and are usually found in the blood or other tissue samples. Examples are alphafetoprotein (AFP), human chorionic gonadotropin, and lactate dehydrogenase (LDH). They may be indicators of tumour stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids. (18 Jul 2002) |
| tumor necrosis factor | <cytokine> Originally described as a tumour inhibiting factor in the blood of animals exposed to bacterial lipopolysaccharide or Bacille Calmette-Guerin. Preferentially kills tumour cells in vivo and in vitro, causes necrosis of certain transplanted tumours in mice and inhibits experimental metastases. Human Tumour Necrosis factor alpha is a protein of 157 amino acids and has a wide range of pro inflammatory actions. Usually considered a cytokine. Synonym: cachectin. Acronym: TNF (13 Nov 1997) |
| arthropathy, neurogenic | Chronic progressive degeneration of the stress-bearing portion of a joint, with bizarre hypertrophic changes at the periphery. It is probably a complication of a variety of neurologic disorders, particularly tabes dorsalis, involving loss of sensation, which leads to relaxation of supporting structures and chronic instability of the joint. (12 Dec 1998) |
| autonomic neurogenic bladder | Malfunctioning bladder, secondary to low spinal cord lesions. (05 Mar 2000) |
| bladder, neurogenic | Any condition of dysfunction of the urinary bladder caused by a lesion of the central or peripheral nervous system. (12 Dec 1998) |
| reflex neurogenic bladder | An abnormal condition of bladder function whereby the bladder is cut off from upper motor neuron control, but where the lower motor neuron arc is still intact. (05 Mar 2000) |
| neurogenic | <embryology> Arising from or caused by the nervous system. Origin: Gr. Gennan = to produce (27 Sep 1997) |
| neurogenic atrophy | Abnormalities of the skin, hair, nails, subcutaneous tissues and bone, caused by peripheral nerve lesions. Synonym: neuritic atrophy, neurogenic atrophy, neurotrophic atrophy, trophic changes. (05 Mar 2000) |
| neurogenic bladder | A dysfunction of the bladder due a malfunction of the autonomic nerves which control bladder function. (27 Sep 1997) |
| neurogenic fracture | A fracture in bone weakened by disease of the nerve supply. (05 Mar 2000) |
| neurogenic gene | Best described in Drosophila, genes that are required to determine a neuronal fate. Examples: Notch, Delta. (18 Nov 1997) |
| neurogenic shock | <neurology> This form of distributive shock results from a change in systemic vascular resistance, mediated by a neurologic injury (for example, head injury, spinal cord injury). Synonym: spinal shock. (27 Sep 1997) |
| neurogenic tonus | Contraction of a muscle caused by the influence of its extrinsic nerve supply (05 Mar 2000) |
| nonneurogenic neurogenic bladder | <urology> Detrusor-sphincter incoordination with urinary incontinence, constipation, urinary tract infection, upper tract changes. Synonym: Hinman syndrome, pseudoneurogenic bladder. (05 Mar 2000) |