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nude mouse a mouse with a genetic defect that prevents them from growing hair and also prevents them from immunologically rejecting human cells and tissues; widely used in preclinical trials
Ãâó: wordnet.princeton.edu/perl/webwn
nude mouse A nude mouse is a genetic mutant that has no thymus gland, and has a severely reduced immune system. The main outward appearance of the mouse is a lack of body hair, which gives it the "nude" nickname. Due to the lack of a thymus, it produces no T cells. The nude mouse is valuable to research because it can be the recipient of many different types of tissues and tumors, as it mounts no rejection response. ...
Ãâó: en.wikipedia.org/wiki/Nude_mouse
nude mouse A type of laboratory mouse that is hairless, lacks a normal thymus gland, and has a defective immune system because of a genetic mutation. Athymic, nude mice are often used in cancer research because they do not reject tumor cells, from mice or other species.
Ãâó: www.stjude.org/glossary
nude mouse an immunodeficient mouse (usually hairless) that has no cell-mediated immunity due to the absence of the thymus gland. They can be used experimentally to grow human tumors.
Ãâó: www.oup.com/uk/booksites/content/0199264724/studen...
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