| nucleotide | <biochemistry> Phosphate esters of nucleosides. The metabolic precursors of nucleic acids are monoesters with phosphate on carbon 5 of the pentose (known as 5' to distinguish sugar from base numbering). However many other structures, such as adenosine 3'5' cyclic monophosphate (cAMP) and molecules with 2 or 3 phosphates are also called nucleotides. (18 Nov 1997) |
|---|---|
| nucleotide 3'-pyrophosphokinase-2',3'-cyclic monophosphokinase | <enzyme> Transfers 5'-beta,gamma-pyrophosphate from ATP and some ATP derivatives to nucleotides and nucleosides at the 3'-hydroxyl group; synthesises the respective 3'-pyrophosphoryl nucleotides Registry number: EC 2.7.6.- Synonym: ppkase (26 Jun 1999) |
| nucleotide binding fold | Protein motif consisting of a fold or pocket with certain conserved residues, required for the binding of nucleotides. (18 Nov 1997) |
| nucleotide deaminases | <enzyme> Catalyze the hydrolysis of nucleotides with the elimination of ammonia. Registry number: EC 3.5.4 (12 Dec 1998) |
| nucleotide deletion | Deletion of a single nucleotide, which in a transcribed gene will lead to a frameshift mutation. Synonym: point deletion. (05 Mar 2000) |
| nucleotide mapping | Two-dimensional separation and analysis of nucleotides. (12 Dec 1998) |
| nucleotide pair | <molecular biology> Two nitrogenous bases (adenine and thymine or guanine and cytosine) held together by weak bonds. Two strands of DNA are held together in the shape of a double helix by the bonds between base pairs. (09 Oct 1997) |
| nucleotide phosphotransferase | <enzyme> Transfers phosphoric acid from an organic phosphate donor to the 2' or 3' hydroxyls of nucleosides and nucleotides Registry number: EC 2.7.1.- (26 Jun 1999) |
| nucleotide pyrophosphate transferase | <enzyme> Transfers the beta, gamma pyrophosphate group from ATP to 3'-hydroxy group of ribonucleotides, oligonucleotides or trna Registry number: EC 2.7.6.- (26 Jun 1999) |
| nucleotides | The basic building blocks of nucleic acids. They are made up of a nitrogen-containing purine or pyrimidine base linked to a sugar (ribose or deoxyribose) and a phosphate group. (14 Nov 1997) |
| adenine nucleotide | A condensation product of adenosine and phosphoric acid; a nucleotide found among the hydrolysis products of all nucleic acids. 3'-Adenylic acid (adenosine 3'-monophosphate) and 5'-adenylic acid (adenosine 5'-monophosphate) differ in the place of attachment of the phosphoric acid to the d-ribose; deoxyadenylic acid differs in having H instead of OH at the 2' position of d-ribose. See: AMP. Synonym: adenine nucleotide. (05 Mar 2000) |
|---|---|
| adenine nucleotide translocase | <enzyme> Catalyses the exchange between endogenous and exogenous adenine nucleotides in mitochondria.ec 2.7.7.-. Registry number: EC 2.7.7.- (12 Dec 1998) |
| cyclic nucleotide | A nucleoside monophosphate in which the phosphoryl group is linked twice to the sugar moiety; e.g., adenosine 3',5'-cyclic monophosphate (cAMP). (05 Mar 2000) |
| cyclic nucleotide-regulated protein kinases | <enzyme> A group of enzymes that catalyses the phosphorylation of serine or threonine residues of proteins and is dependent on cyclic nucleotides. Registry number: EC 2.7.10.- (12 Dec 1998) |
| xanthine nucleotide | The monophosphoric ester of xanthosine. An intermediate in GMP biosynthesis. Synonym: xanthidylic acid, xanthine nucleotide, xanthylic acid. (05 Mar 2000) |
| pyrimidine-5'-nucleotide nucleosidase | <enzyme> Also acts on some deoxyribonucleotides Registry number: EC 3.2.2.10 Synonym: pyr-5'-nt-nucleosidase (26 Jun 1999) |
| nicotinamide-nucleotide adenylyltransferase | <enzyme> An enzyme that catalyses reversibly the transfer of the adenylyl moiety of ATP to the phosphoryl group of nmn to form NAD+ and pyrophosphate. The enzyme is found predominantly in the nuclei and catalyses the final reaction in the major pathway for the biosynthesis of NAD in mammals. Chemical name: ATP:nicotinamide-nucleotide adenylyltransferase Registry number: EC 2.7.7.1 (12 Dec 1998) |
| diphosphopyridine nucleotide | nAD |
| thymine nucleotide | A major constituent of DNA. Synonym: thymidine 5'-monophosphate, thymine nucleotide. (05 Mar 2000) |
| triphosphopyridine nucleotide | Former name for nicotinamide adenine dinucleotide phosphate. (05 Mar 2000) |
| flavin nucleotide | <biochemistry> Flavin derivatives that act as prosthetic groups (covalently linked cofactors) for flavin enzymes. (18 Nov 1997) |
| 2',3'-cyclic nucleotide 2'-phosphodiesterase | <enzyme> Catalyses the hydrolysis of the 2'-phosphodiesterase bond to yield nucleoside 3'phosphate Registry number: EC 3.1.4.16 Synonym: 2',3'-cyclic nucleotide 2'-phosphohydrolase (26 Jun 1999) |
| 2',3'-cyclic nucleotide 3'-phosphodiesterase | <enzyme> Catalyses the hydrolysis of the 3'-phosphoesterase bond to yield nucleoside 2'-phosphate Registry number: EC 3.1.4.37 Synonym: 2',3'-cyclic nucleotide 3'-phosphohydrolase, 2',3'-cn phosphodiesterase, 2',3'-cnpase (26 Jun 1999) |
| 2',3'-cyclic-nucleotide phosphodiesterases | <enzyme> Nucleoside-2',3'-cyclic phosphate nucleotidohydrolase. Enzymes that catalyze the hydrolysis of the 2'- or 3'- phosphate bonds of 2',3'-cyclic nucleotides. Also hydrolyzes nucleoside monophosphates. Registry number: EC 3.1.4.- (12 Dec 1998) |
| 3',5'-cyclic-nucleotide phosphodiesterase | <enzyme> An enzyme that catalyses the hydrolysis of cyclic AMP to form adenosine 5'-phosphate. The enzyme is widely distributed in animal tissue and controls the level of intracellular cyclic AMP. Also acts on 3',5'-cyclic imp and 3',5'-cyclic GMP. Chemical name: 3',5'-Cyclic-nucleotide 5'-nucleotidohydrolase Registry number: EC 3.1.4.17 (12 Dec 1998) |