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NOS <enzyme> An enzyme that catalyses the conversion of l-arginine, NADPH, and oxygen to citrulline, nitric oxide, and NADP+.
The enzyme found in brain, but not that induced in lung or liver by endotoxin, requires calcium.There are two isoforms, one constitutive and one activated by calmodulin.
Chemical name: L-Arginine,NADPH:oxygen oxidoreductase (nitric-oxide-forming)
Registry number: EC 1.14.13.39
Acronym: NOS
(12 Dec 1998)
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