| blood transfusion reaction | This refers to an immune response against transfused blood cells. Antigens, on the surface of red blood cells, are recognised as foreign proteins and can stimulate sensitised lymphocytes to produce antibodies to the red blood cell antigens. This triggers a complex immunological reaction that results in the destruction of the transfused red blood cell. The blood groups (A, B, AB, O) are classified on the basis of the presence of surface antigens on the red blood cell. Type A blood has A antigens. The plasma component of the blood contains the antibodies against all other blood group antigens other that its own. Another type of surface antigen is known as Rh factor. Rh factor is either present (Rh positive) or absent (Rh negative). Rh compatibility is another requirement for blood transfusion. Symptoms and findings of a transfusion reaction include flank pain, fever, chills, bloody urine, rash, low blood pressure, dizziness and fainting. (27 Sep 1997) |
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| incompatible blood transfusion reaction | A syndrome due to intravascular haemolysis of transfused blood by serum antibodies of the recipient, which react with an antigen of the donor red cells; characterised by chills, fever (often with urticaria), backache or muscle cramps, haemoglobinaemia, haemoglobinuria, and oliguria, which may result in acute renal failure, DIC, and death. (05 Mar 2000) |
| transfusion reaction | A reaction to a blood transfusion secondary to some incompatibility in type, RH factor or other surface antigens. May be manifest by haemolytic anaemia, heart failure, and-or renal failure. Symptoms include facial flushing, angioedema, headache, wheezing, anaphylaxis, shock, fever, chills and breathing difficulty. (27 Sep 1997) |
| acute febrile illness | An illness of sudden onset that manifests with fever. (27 Sep 1997) |
| acute febrile neutrophilic dermatosis | A rare dermatosis, predominant in women, of rapid onset and characterised by plaque-like lesions, usually multiple, on the face, neck, and upper extremities, accompanied by conjunctivitis, mucosal lesions, fever, malaise, arthralgia, and peripheral blood neutrophilia in many cases; biopsy reveals polymorphonuclear infiltrate of the dermis; rapid remission occurs with systemic steroid therapy. Synonym: Sweet's disease. (05 Mar 2000) |
| complex febrile convulsion | A febrile convulsion that is prolonged (greater than 15 minutes' duration) or is associated with focal neurological deficits. (05 Mar 2000) |
| convulsions, febrile | Seizures occurring in young children during febrile episodes due to a low convulsive threshold. The convulsions are usually a self-limiting disorder after the age of 5 years. (12 Dec 1998) |
| hydroa febrile | <virology> The Herpes simplex virus is responsible for several different infections in humans: gingivostomatitis (in children), pharyngitis, oral and lip lesions (recurrent Herpes simplex type 1), proctitis, (type 2) and genital herpes (type 2). (27 Sep 1997) |
| systemic febrile diseases | Generic term for diseases characterised by fever. (05 Mar 2000) |
| febrile | <symptom> Pertaining to or characterised by fever. Origin: L. Febrilis (18 Nov 1997) |
| febrile agglutinins | <investigation> A serologic fluorescent antibody screen that indicates infection with the rickettsial bacteria which is responsible for Rocky Mountain spotted fever. This test may also be positive in brucellosis, salmonella infection and tularaemia. (27 Sep 1997) |
| febrile albuminuria | Albuminuria associated with fever. (05 Mar 2000) |
| febrile convulsion | A brief seizure, lasting less than 15 minutes, seen in a neurologically normal infant or young child, associated with fever. Synonym: febrile seizure. (05 Mar 2000) |
| febrile crisis | The stage in a febrile disease when spontaneous defervescence occurs. (05 Mar 2000) |
| febrile psychosis | A psychosis following an acute infection, shock, or chronic intoxication; begins as delirium followed by pronounced mental confusion with hallucinations and unsystematised delusions, and sometimes stupor. Synonym: febrile psychosis. (05 Mar 2000) |