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nondisjunction <genetics, molecular biology> Failure of homologous chromosomes or sister chromatids to separate or segregate at meiosis or mitosis respectively. It results in aneuploid cells, where the daughter cell has two chromosomes or two chromatids and the other has none.
Nondisjunction of the X chromosome in Drosophila confirmed the theory of chromosomal inheritance.
(17 Jul 2002)
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meiotic nondisjunction Failure of two memberrs of a chromosome pair to separate (disjoin) during meiosis so that both go to one daughter cell and none to the other. This mechanism is responsible for the extra chromosome 21 in trisomy 21 (down syndrome) and for extra and missing chromosomes causing other birth defects and many spontaneous abortions (miscarriages).
(12 Dec 1998)
mitotic nondisjunction Failure of the two members of a chromosome pair to separate (disjoin) during mitosis so that both go to one daughter cell and none to the other.
(12 Dec 1998)
primary nondisjunction Nondisjunction occurring in a previously normal cell.
(05 Mar 2000)
secondary nondisjunction Nondisjunction occurring in an aneuploid cell that was the result of a primary nondisjunction.
(05 Mar 2000)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 1 ÆäÀÌÁö: 1
  • Nondisjunction, Genetic - »õâ The failure of homologous CHROMOSOMES or CHROMATIDS to segregate during MITOSIS or MEIOSIS with the result that one daughter cell has both of a pair of parental chromosomes or chromatids and the other has none.
    Synonyms : Genetic Non-Disjunction, Genetic Nondisjunction, Non-Disjunction, Genetic, Genetic Non Disjunction, Genetic Non-Disjunctions, Genetic Nondisjunctions, Non Disjunction, Genetic, Non-Disjunctions, Genetic, Nondisjunctions, Genetic
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nondisjunction meiosis in which there is a failure of paired homologous chromosomes to separate; results in an abnormal number of chromosomes in the daughter cells
Ãâó: wordnet.princeton.edu/perl/webwn
nondisjunction an error that occurs during the division of sex chromosomes, causing either too much or too little genetic information to be placed in an egg or sperm when it is formed
Ãâó: www.american-depot.com/services/resources_gl_n.asp
nondisjunction A failure of homologous chromosomes or sister chromatids to separate at anaphase.
Ãâó: www.modernhumanorigins.com/n.html
nondisjunction an error in cell division where the chromosomes fail to disjoin, so that both pass to the same daughter cell.
Ãâó: www.uchicagokidshospital.org/online-library/conten...
nondisjunction failure of two homologous chromosomes to pass to separate cells during the first division of meiosis, or the two chromatids to pass to separate cells during the second meiotic division. As a result, one daughter cell has two chromosomes or chromotids while the other has none
Ãâó: www.storknet.com/complications/glossary.htm
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nondisjunction meiosis in which there is a failure of paired homologous chromosomes to separate
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