| Rothera's nitroprusside test | A test for ketone bodies; 5 ml of fresh urine are saturated with solid ammonium sulfate and mixed with 10 drops of freshly prepared 2% sodium nitroprusside solution, which is then mixed with 10 drops of concentrated ammonia water and allowed to stand for 15 min; the presence of acetoacetic acid, or of larger concentrations of acetone, is indicated by the development of a blue-purple colour. (05 Mar 2000) |
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| cyanide-nitroprusside test | A qualitative test for diagnosis of cystinuria; the addition of fresh sodium cyanide formed by sodium nitroprusside to a sample of urine gives rise to a stable red-purple colour in the presence of cystine. (05 Mar 2000) |
| sodium nitroprusside | (Na2FeCCN)5NO-5H2O;a rapidly acting and potent arterial and venous vasodilator used in hypertensive emergencies and administered intravenously. Acts in a manner similar to vasodilator nitrates and nitrites by donating nitric oxide which produces vasodilation; also used as a reagent for detection of organic compounds in the urine. Synonym: sodium nitroferricyanide. (05 Mar 2000) |
| nitroprusside | <chemical> (oc-6-22)-pentakis(cyano-c)nitrosoferrate(2-). A powerful vasodilator used in emergencies to lower blood pressure or to improve cardiac function. It is also an indicator for free sulfhydryl groups in proteins. Pharmacological action: antihypertensive agents, indicators and reagents, sulfhydryl reagents, vasodilator agents. Chemical name: Ferrate(2-), pentakis(cyano-C)nitrosyl-, (OC-6-22)- (12 Dec 1998) |
| nitroprusside test | A qualitative test for cystinuria; following the addition of sodium cyanide to the urine, the further addition of nitroprusside produces a red-purple colour if the cyanide has reduced any cystine present to cysteine. (05 Mar 2000) |