| nicotinamidase | <enzyme> An enzyme that catalyses the hydrolysis of nicotinamide to nicotinate and ammonia. Chemical name: Nicotinamide amidohydrolase Registry number: EC 3.5.1.19 (12 Dec 1998) |
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| nicotinamide | <biochemistry> Member of the water soluble B vitamin group, used in the production of fatty acids, steroids and cholesterol, deficiency is known as pellagra. Has cholesterol-lowering and vasodilating properties. (27 Sep 1997) |
| nicotinamide adenine dinucleotide | <enzyme> Coenzymes that act as electron and hydrogen carriers in some oxidation-reduction reactions. (09 Oct 1997) |
| nicotinamide adenine dinucleotide phosphate | See: NADP. (18 Nov 1997) |
| nicotinamide methyltransferase | <enzyme> Catalyses reversibly the methylation of nicotinamide in the presence of s-adenosylmethionine to yield 1-methylnicotinamide and s-adenosylhomocysteine Registry number: EC 2.1.1.1 Synonym: nicotinamide methylase, nicotinamide-s-adenosylmethionine methyltransferase (26 Jun 1999) |
| nicotinamide mononucleotide | <chemical> 3-carbamoyl-1-beta-d-ribofuranosyl pyridinium hydroxide-5'phosphate, inner salt. A nucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of d-ribose. Synonym: nicotinamide ribonucleotide; nmn. Chemical name: Pyridinium, 3-(aminocarbonyl)-1-(5-O-phosphono-beta-D-ribofuranosyl)-, inner salt (12 Dec 1998) |
| nicotinamide phosphoribosyltransferase | <enzyme> Utilises nicotinamide, mg(2+), prpp and ATP Registry number: EC 2.4.2.12 Synonym: nmn pyrophosphorylase (26 Jun 1999) |
| nicotinamide riboside kinase | <enzyme> Phosphorylates 3-deazaguanosine and tiazofurin Registry number: EC 2.7.1.- (26 Jun 1999) |
| nicotinamide-nucleotide adenylyltransferase | <enzyme> An enzyme that catalyses reversibly the transfer of the adenylyl moiety of ATP to the phosphoryl group of nmn to form NAD+ and pyrophosphate. The enzyme is found predominantly in the nuclei and catalyses the final reaction in the major pathway for the biosynthesis of NAD in mammals. Chemical name: ATP:nicotinamide-nucleotide adenylyltransferase Registry number: EC 2.7.7.1 (12 Dec 1998) |
| nicotinate | Salt or ester of nicotinic acid; some nicotinate's are used in ointments as rubefacients. (05 Mar 2000) |
| nicotinatenucleotide-dimethylbenzimidazole phosphoribosyltransferase | <enzyme> Involved in the synthesis of adenosyl-cobalamin (coenzyme b12); amino acid sequence given in second source Registry number: EC 2.4.2.21 Synonym: nicotinate ribonucleotide benzimidazole phosphoribosyltransferase, trans-n-glycosidase, nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, cobu gene product, cobt protein, scobt protein, cobt gene product (26 Jun 1999) |
| nicotine | <drug> A plant alkaloid from tobacco, blocks transmission at nicotinic synapses. (18 Nov 1997) |
| nicotine dehydrogenase | <enzyme> Mo-pterin-fe-s cluster- and fad-dependent enzyme composed of 3 unequal polypeptides; catalyses the conversion of nicotine, acceptor, and water to (s)-6-hydroxynicotine and reduced acceptor Registry number: EC 1.5.99.4 (26 Jun 1999) |
| nicotine oxidase | <enzyme> Cytochrome p-450 enzyme Registry number: EC 1.5.3.- (26 Jun 1999) |
| nicotine stomatitis | Heat stimulated lesions, usually on the palate, that begin with erythema and progress to multiple white papules with a red dot in the centre. The red dot represents a dilated, inflamed salivary duct orifice. (05 Mar 2000) |