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| NMB | neuromedin B; neuromuscular blockade; neuromuscular blocking; neuromuscular blocker/blocking [drug, ... |
|---|---|
| Ca2+-blocker | calcium channel blocker |
| NMT | neuromuscular tension; neuromuscular transmission; N-methyltransferase; N-myristoyltransferase; no m... |
| BB | bad breath; bed bath; beta blockade, beta blocker; BioBreeding [rat]; blanket bath; blood bank; bloo... |
| BHAT | Beta Blocker Heart Attack Trial |
| ARB | angiotensin receptor blocker |
|---|---|
| ARB | Angiotensin II receptor blocker |
| BHAT | Beta-Blocker Heart Attack Trial |
| CCB | Calcium channel blocker |
| CEB | Calcium entry blocker |
| alpha-blocker | An agent that competitively blocks alpha-adrenergic receptors; used in the treatment of hypertension. Synonym: alpha-blocker. (05 Mar 2000) |
|---|---|
| beta-blocker | <pharmacology> A large group of medications that act to block specific receptors in the nervous system. A drug that induces adrenergic blockade at either á1 or á2 adrenergic receptors or at both. The effect of beta-blockade results in slowing of the heart rate, reduction in blood pressure and reduced anxiety. Beta-blockers are used in the treatment of angina, heart arrhythmias, high blood pressure, mitral valve prolapse and other conditions. (06 Oct 1997) |
| blocker | 1. An instrument used to obstruct a passage. See: blocking agent. (05 Mar 2000) |
| calcium channel-blocker | <pharmacology> A class of drugs that act by selective inhibition of calcium ion influx through or across cell membranes or on the release and binding of calcium in intracellular pools. Calcium channel blockers are used primarily in the treatment of certain heart conditions and stroke. As they are inducers of vascular and other smooth muscle relaxation, they are also used in the treatment of hypertension and cerebrovascular spasms, as myocardial protective agents, and in the relaxation of uterine spasms. Synonym: calcium antagonist, calcium channel-blocker, slow channel-blocking agent. (12 May 2002) |
| medication, beta-blocker | Drugs that antagonise the action of adrenaline (a beta adrenergic substance) and relieve stress to the heart muscle. Beta-blockers are often used to slow the heart rate or lower the blood pressure. (12 Dec 1998) |
| H2 blocker | <pharmacology> A class of anti-ulcer medication which work through the inhibition of basal and nocturnal gastric acid secretion by competitive inhibition of the action of histamine at histamine H2 receptor sites on the parietal cells. Drugs of this type block gastric acid secretion and are therefore clinically useful in treating duodenal ulcers. Examples include cimetidine (Tagamet), famotidine (Pepcid), nizatidine (Axid) and ranitidine (Zantac). (27 Sep 1997) |
| neuromuscular | <anatomy> Pertaining to muscles and nerves. (18 Nov 1997) |
| neuromuscular agents | Drugs used for their actions on skeletal muscle. Included are agents that act directly on skeletal muscle, those that alter neuromuscular transmission (neuromuscular blocking agents), and drugs that act centrally as skeletal muscle relaxants (muscle relaxants, central). Drugs used in the treatment of movement disorders are anti-dyskinesia agents. (12 Dec 1998) |
| neuromuscular blockade | The intentional interruption of transmission at the neuromuscular junction by external agents, usually neuromuscular blocking agents. It is distinguished from nerve block in which nerve conduction is interrupted rather than neuromuscular transmission. Neuromuscular blockade is commonly used to produce muscle relaxation as an adjunct to anaesthesia during surgery and other medical procedures. It is also often used as an experimental manipulation in basic research. It is not strictly speaking anaesthesia but is grouped here with anaesthetic techniques. The failure of neuromuscular transmission as a result of pathological processes is not included here. (12 Dec 1998) |
| neuromuscular blocking agent | A group of drugs that prevent motor nerve endings from exciting skeletal muscle. They act either by competing for the neurotransmitter, acetylcholine, (like D-tubocurarine, mivacurium and pancuronium), or by first stimulating the postjunctional muscle membrane and subsequently desensitizing the muscle endplates to the acetylcholine (like succinylcholine or decamethonium); used in surgery to produce paralysis and facilitate manipulation of muscles. (05 Mar 2000) |
| neuromuscular blocking agents | Drugs that interrupt transmission of nerve impulses at the skeletal neuromuscular junction. They can be of two types, competitive, stabilizing blockers (neuromuscular nondepolarising agents) or noncompetitive, depolarising agents (neuromuscular depolarising agents). Both prevent acetylcholine from triggering the muscle contraction and they are used as anaesthesia adjuvants, as relaxants during electroshock, in convulsive states, etc. (12 Dec 1998) |
| neuromuscular cell | A cell of a lower metazoan organism that is both sensitive and contractile. (05 Mar 2000) |
| neuromuscular depolarising agents | Drugs that interrupt transmission at the skeletal neuromuscular junction by causing sustained depolarisation of the motor end plate. These agents are primarily used as adjuvants in surgical anaesthesia to cause skeletal muscle relaxation. (12 Dec 1998) |
| neuromuscular junction | A chemical synapse between a motoneuron and a muscle fibre. Synonym: motor end plate. (18 Nov 1997) |
| neuromuscular nondepolarising agents | Drugs that interrupt transmission at the skeletal neuromuscular junction without causing depolarisation of the motor end plate. They prevent acetylcholine from triggering muscle contraction and are used as muscle relaxants during electroshock treatments, in convulsive states, and as anaesthesia adjuvants. (12 Dec 1998) |
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