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neuroleptic <pharmacology> A term coined to refer to the effects on cognition and behaviour of antipsychotic drugs, which produce a state of apathy, lack of initiative and limited range of emotion and in psychotic patients cause a reduction in confusion and agitation and normalisation of psychomotor activity.
Origin: Gr. Lepsis = a taking hold
(18 Nov 1997)
neuroleptic agent Any of a family of drugs producing sedation and tranquilization (e.g., chlorpromazine, haloperidol).
See: antipsychotic agent.
Synonym: neuroleptic.
(05 Mar 2000)
neuroleptic drugs Literally nerve seising: used of chlorpromazine like drugs. Antagonise the effects of dopamine.
Origin: Gr. Lepsis = a taking hold
(18 Nov 1997)
neuroleptic malignant syndrome <syndrome> This describes the combination of catatonic rigidity, stupor, unstable blood pressure, fever, profuse sweating, sweating and incontinence as a reaction to antipsychotic agents (phenothiazines) in therapeutic doses.
Origin: Gr. Lepsis = a taking hold
(27 Sep 1997)
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