| neuroendocrine transducer cell | An endocrine cell that releases its hormonal product into the bloodstream only upon receipt of a nervous impulse. (05 Mar 2000) |
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| transducer cell | Any cell responding to a mechanical, thermal, photic, or chemical stimulus by generating an electrical impulse synaptically transmitted to a sensory neuron in contact with the cell. (05 Mar 2000) |
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| neuroendocrine cell | <endocrinology> A hormone secreted by specialised neurons (neuroendocrine cells), for example releasing hormones. (18 Nov 1997) |
| transducer | <physics> A device that transforms one type of energy to another. (17 Mar 1998) |
| transmembrane transducer | A system that transmits a chemical or electrical signal across a membrane. Usually involves a transmembrane receptor protein that is thought to undergo a conformation change that is expressed on the inner surface of the membrane. Many such transducing species are dimeric and the conformation change may involve interaction between the two components. (18 Nov 1997) |
| carcinoma, neuroendocrine | A group of carcinomas which share a characteristic morphology, often being composed of clusters and trabecular sheets of round "blue cells", granular chromatin, and an attenuated rim of poorly demarcated cytoplasm. Neuroendocrine tumours include carcinoids, small ("oat") cell carcinomas, medullary carcinoma of the thyroid, merkel cell tumour, cutaneous neuroendocrine carcinoma, pancreatic islet cell tumours, and pheochromocytoma. Neurosecretory granules are found within the tumour cells. (12 Dec 1998) |
| primary neuroendocrine carcinoma of the skin | A rare malignant cutaneous tumour seen in sun-exposed skin of elderly patients composed of dermal nodules of small round cells with scanty cytoplasm in a trabecular pattern; the tumour cells contain cytoplasmic dense core granules resembling neurosecretory granules seen in Merkel cells. Synonym: primary neuroendocrine carcinoma of the skin, trabecular carcinoma. (05 Mar 2000) |
| neuroendocrine | 1. Pertaining to the anatomical and functional relationships between the nervous system and the endocrine apparatus. 2. Descriptive of cells that release a hormone into the circulating blood in response to a neural stimulus. Such cells may comprise a peripheral endocrine gland (e.g., the insulin-secreting beta cells of the islets of Langerhans in the pancreas and the adrenaline-secreting chromaffin cells of the adrenal medulla); others are neurons in the brain (e.g., the neurons of the supraoptic nucleus that release antidiuretic hormone from their axon terminals in the posterior lobe of the hypophysis). (05 Mar 2000) |
| neuroendocrine tumours | Tumours whose cells possess secretory granules and originate from the neuroectoderm, i.e., the cells of the ectoblast or epiblast that program the neuroendocrine system. Common properties across most neuroendocrine tumours include ectopic hormone production (often via apud cells), the presence of tumour-associated antigens, and isozyme composition. (12 Dec 1998) |
| T-cell-rich, B-cell lymphoma | <tumour> A B-cell lymphoma in which more than 90% of the cells are of T-cell origin, masking the large cells that form the neoplastic B-cell component. See: adult T-cell lymphoma. (05 Mar 2000) |
| absorption cell | A small glass chamber with parallel sides, in which absorption spectra of solutions can be obtained. (05 Mar 2000) |
| acid cell | One of the cell's of the gastric glands; it lies upon the basement membrane, covered by the chief cell's, and secretes hydrochloric acid that reaches the lumen of the gland through fine intracellular and intercellular canals (canaliculi). Synonym: acid cell, oxyntic cell. (05 Mar 2000) |
| acidophil cell | A cell whose cytoplasm or its granules stain with acid dyes. (05 Mar 2000) |
| acinar cell | Any secreting cell lining an acinus, especially applied to the cell's of the pancreas that furnish pancreatic juice and enzymes to distinguish them from the cell's of ducts and the islets of Langerhans. Synonym: acinous cell. (05 Mar 2000) |
| acinar cell tumour | A solid and cystic tumour of the pancreas, occurring in young women; tumour cells contain zymogen granules. (05 Mar 2000) |
| acinic cell adenocarcinoma | <tumour> An adenocarcinoma arising from secreting cells of a racemose gland, particularly the salivary glands. Synonym: acinar carcinoma, acinic cell carcinoma, acinose carcinoma, acinous carcinoma. (05 Mar 2000) |