| multiple intestinal polyposis | Begins usually in late childhood; polyps increase in numbers, causing symptoms of chronic colitis, and carcinoma of the colon almost invariably develops in untreated cases; autosomal dominant inheritance. In the Gardner syndrome there are extracolonic changes (desmoid tumours, etc.). Synonym: polyposis coli. Hamartomatous polyposis of the small or large intestine, Peutz-Jeghers syndrome with melanin spots on the lips, less common, miscellaneous, rare, and doubtful occurrences. Synonym: familial intestinal polyposis. (05 Mar 2000) |
|---|---|
| familial adenomatous polyposis | <gastroenterology> Genetic disease with numerous precancerous polyps in the colon and rectum. Also called familial polyposis. (12 Dec 1998) |
| familial intestinal polyposis | Begins usually in late childhood; polyps increase in numbers, causing symptoms of chronic colitis, and carcinoma of the colon almost invariably develops in untreated cases; autosomal dominant inheritance. In the Gardner syndrome there are extracolonic changes (desmoid tumours, etc.). Synonym: polyposis coli. Hamartomatous polyposis of the small or large intestine, Peutz-Jeghers syndrome with melanin spots on the lips, less common, miscellaneous, rare, and doubtful occurrences. Synonym: familial intestinal polyposis. (05 Mar 2000) |
| familial polyposis | An inherited condition in which several hundred polyps develop in the colon and rectum. (12 Dec 1998) |
| familial polyposis coli | <gastroenterology, oncology> A inherited, disorder where there are multiple adenomatous polyps (up to several thousand) in the colon. Malignant degeneration of the polyps (to colon carcinoma) occurs in virtually 100% by age 40. Inheritance: autosomal dominant. (27 Sep 1997) |
| familial multiple endocrine adenomatosis | The presence of functioning tumours in more than one endocrine gland, commonly the pancreatic islets and parathyroid glands, which may be associated with Zollinger-Ellison syndrome; dominant inheritance. Synonym: multiple endocrine adenomatosis. (05 Mar 2000) |
| adenomatous polyposis coli | An autosomal dominant polyposis syndrome in which the colon contains few to thousands of adenomatous polyps, often occurring by age 15 to 25. (12 Dec 1998) |
| polyposis | Presence of several polyps. Origin: polyp + G. -osis, condition (05 Mar 2000) |
| polyposis coli | Hereditary disorder (Mendelian dominant) characterised by the development of hundreds of adenomatous polyps in the large intestine, which show a tendency to progress to malignancy. The APC gene has also been implicated in a chromosome 5 gastric and pancreatic cancer. (18 Nov 1997) |
| polyposis syndromes | <radiology> Inher. Malig. Type familial polyposis coli dom and adenoma Gardner syndrome dom and Turcot syndrome rec CNS Peutz-Jeghers syndrome dom (+) hamartoma Cowden syndrome dom ? juvenile polyposis coli (?) - juvenile Cronkhite-Canada syndrome (12 Dec 1998) |
| juvenile polyposis coli | <radiology> Benign polyposis, inheritance uncertain, inflammatory or retention polyps: round, smooth, soft, mucin-filled, non-neoplastic, onset less than 10 yrs, polyps can prolapse through anus, associated with diarrhoea, protein loss see: polyposis syndromes, Cronkhite-Canada syndrome (12 Dec 1998) |
| filiform polyposis | <radiology> Benign, non-specific sequela of diffuse, severe mucosal inflammation, UC, Crohn's, XR: thin, straight filling defects, resembles stalks of polyps without heads (12 Dec 1998) |
| abortion, multiple | Couples who have had 2 or more miscarriages (spontaneous abortions) have about a 5% chance that one member of the couple is carrying a chromsome translocation responsible for the miscarriages. (12 Dec 1998) |
| advanced multiple-beam equalization radiography | A variant of scanning equalization radiography using several X-ray beams. (05 Mar 2000) |
| amyloidosis of multiple myeloma | Foci of amyloidosis in mesenchymal tissues of some persons with multiple myeloma; no direct relation between amyloid and Bence Jones protein is conclusively known. (05 Mar 2000) |