| multicentric | Having many centres. A multicentric cancer consists of a primary tumour with satellites of cancerous growth in surrounding tissues. The basis for adjuvant radiation therapy after, for instance, a lumpectomy is to irradiate the satellite tumours, should any exist. (16 Dec 1997) |
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| multicentric reticulohistiocytosis | <radiology> Females, middle age, deposition arthropathy, bilaterally symmetric involvement of hands, soft-tissue swelling, well-circumscribed marginal bony erosions Differential diagnosis: RA -- juxta-articular osteoporosis, DIPs spared, psoriasis -- asymmetric, ill-defined erosions, new bone, gout -- overhanging edges, asymmetric (12 Dec 1998) |