| multicentric | Having many centres. A multicentric cancer consists of a primary tumour with satellites of cancerous growth in surrounding tissues. The basis for adjuvant radiation therapy after, for instance, a lumpectomy is to irradiate the satellite tumours, should any exist. (16 Dec 1997) |
|---|---|
| multicentric reticulohistiocytosis | <radiology> Females, middle age, deposition arthropathy, bilaterally symmetric involvement of hands, soft-tissue swelling, well-circumscribed marginal bony erosions Differential diagnosis: RA -- juxta-articular osteoporosis, DIPs spared, psoriasis -- asymmetric, ill-defined erosions, new bone, gout -- overhanging edges, asymmetric (12 Dec 1998) |
| parosteal osteosarcoma | <tumour> Low grade osteosarcoma arising on the surface of bone without involvement of the underlying marrow, usually occurring as a heavily ossified mass of the distal femur in women in the third and fourth decades of life. (05 Mar 2000) |
| periosteal osteosarcoma | <tumour> Chondroblastic osteosarcoma occurring on the surface of bones without involvement of the marrow; usually presents in adolescents and young adults as a lucent defect with bone spicules extending into soft tissues. Histologically, the tumour is intermediate to high grade, and the cartilage is lobulated. (05 Mar 2000) |
| osteosarcoma | <oncology, tumour> Malignant tumour of bone (probably neoplasia of osteocytes). (18 Nov 1997) |
| osteosarcoma, juxtacortical | A form of osteogenic sarcoma of relatively low malignancy, probably arising from the periosteum and initially involving cortical bone and adjacent connective tissue. It occurs in middle-aged as well as young adults and most commonly affects the lower part of the femoral shaft. (12 Dec 1998) |