| drug-drug interaction | The effects that occur when two or more drugs are used together. Such effects include changes of absorption in the digestive tract, changes in rate of the drugs' breakdown in the liver, new or enhanced side effects and changes in the drugs' activity. (09 Oct 1997) |
|---|---|
| morphine | <drug> An opioid alkaloid, isolated from opium, with a complex ring structure. It is a powerful analgesic with important medical uses, but is highly addictive. Functions by occupying the receptor sites for the natural neurotransmitter peptides, endorphins and enkephalins, but is stable to the peptidases that inactivate these compounds. Pharmacologic action: Narcotic analgesia, increases venous capacitance and reduces systemic vascular resistance. Uses: Analgesic for ischemic chest pain, hemodynamic changes lead to reduced pulmonary congestion, reduced myocardial oxygen demand. Dose: 1-3 mg slow IV increments until desired effect. Potential complications: Respiratory depression, hypotension, especially in hypovolemic patients. (17 Mar 2000) |
| morphine 6-dehydrogenase | <enzyme> Catalyses the dehydrogenation of morphine in position 6 to morphinone; also acts on codeine, normorphine and ethylmorphine Registry number: EC 1.1.1.218 Synonym: naloxone reductase (26 Jun 1999) |
| morphine dependence | Strong dependence, both physiological and emotional, upon morphine. (12 Dec 1998) |
| morphine derivatives | Analogs or derivatives of morphine. (12 Dec 1998) |
| morphine hydrochloride | White acicular or cubical crystals of bitter taste, soluble in about 25 parts of water. (05 Mar 2000) |
| morphine injector's septicaemia | Blood stream infection in an individual who injects him or herself with narcotics, usually intravenously, due to bacterial contamination of equipment used. Seen more often with heroin and narcotics other than morphine. (05 Mar 2000) |
| morphine sulfate | Morphine used for formulation of tablets as well as solutions for parenteral, epidural, or intrathecal injection to relieve pain. (05 Mar 2000) |
| african swine fever-like viruses | An unnamed, unclassified genus of DNA viruses with a single species: african swine fever virus. (12 Dec 1998) |
| anterior pituitary-like hormone | A glycoprotein with a carbohydrate fraction composed of d-galactose and hexosamine, extracted from the urine of pregnant women and produced by the placental trophoblastic cells; its most important role appears to be stimulation, during the first trimester, of ovarian secretion of the oestrogen and progesterone required for the integrity of conceptus; it appears to play no significant role in the last two trimesters of pregnancy, as the oestrogen and progesterone are then formed by the placenta. Synonym: anterior pituitary-like hormone, choriogonadotropin, chorionic gonadotropic hormone, chorionic gonadotrophic hormone, placenta gonadotropin, placentagonadotropin. (05 Mar 2000) |
| Artemia trypsin-like proteinase | <enzyme> Cysteine proteinase involved in lipovitellin degradation Registry number: EC 3.4.22.- (26 Jun 1999) |
| box-like heart | <radiology> Ebstein's anomaly, massive cardiomegaly, primarily RA enlargement (12 Dec 1998) |
| broom-like | <botany> Describes a plant which has many branches parallel or almost so and usually erect. (09 Oct 1997) |
| gallus adeno-like virus | A virus with characteristics of adenovirus, not known to be associated with natural disease. Synonym: gallus adeno-like virus. (05 Mar 2000) |
| GCK-like kinase | <enzyme> Similar to human germinal centre kinase. Registry number: EC 2.7.1.- Synonym: glk kinase (26 Jun 1999) |