| leukemia | <haematology> An acute or chronic disease of unknown cause in man and other warm blooded animals that involves the blood forming organs, is characterised by an abnormal increase in the number of leucocytes in the tissues of the body with or without a corresponding increase of those in the circulating blood and is classified according of the type leucocyte most prominently involved. (18 Nov 1997) |
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| acute monocytic leukaemia | <haematology> The most common translocation in this disorder of poorly differentiated monocytic cells involves chromosome region 11q in a large percentage of cases. The translocation involves a cellular oncogene, c-ets which is mapped to the 11q23-24 region. The most common translocations reported are t(6;11), t(9;11), t(11;17) and t(11;19), of which t(9;11) (p21-22;q23) is by far the most frequently detected and implicated in acute myeloid leukaemia. The cells express CD14 surface antigen, which is diagnostic of monocytic cells. Acronym: AML Classification: FAB M5 (07 Apr 1998) |
| monocytic angina | An obsolete term for infectious mononucleosis. (05 Mar 2000) |
| monocytic leukaemia | Cancer of the blood due to proliferation of cells of the monocyte series. Origin: Gr. Haima = blood (13 Nov 1997) |
| monocytic leukemoid reaction | Leukocytosis of varying degree, e.g., 30,000 to 40,000 per cu mm, with adult monocytes and immature forms amounting to 30% (or more) of the total number of white blood cells in the circulating blood; may be observed in association with tuberculosis, especially the first infection, miliary type. (05 Mar 2000) |
| monocytic leukocytosis | An abnormal increase in the number of monocytes in the circulating blood. Synonym: monocytic leukocytosis. (05 Mar 2000) |
| monocytic leukopenia | Diminution in the number of monocytes in the circulating blood. Synonym: monocytic leukopenia, monopenia. Origin: mono-+ G. Kytos, cell, + penia, poverty (05 Mar 2000) |
| Schilling type of monocytic leukaemia | See: monocytic leukaemia. (05 Mar 2000) |
| Naegeli type of monocytic leukaemia | A variant of granulocytic leukaemia with monocytosis in the peripheral blood. Synonym: Naegeli type of monocytic leukaemia. (05 Mar 2000) |
| equine monocytic ehrlichiosis | <veterinary> A febrile disease of horses in North America caused by Ehrlichia risticii and characterised by anorexia, leukopenia, and occasional diarrhoea. Synonym: Potomac horse fever. (05 Mar 2000) |