| Moloney murine leukaemia virus | <molecular biology, virology> Replication competent retrovirus (Oncovirinae) that causes leukaemia in mice, isolated by Moloney from cell free extracts made from a transplantable mouse sarcoma. (18 Nov 1997) |
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| Moloney murine sarcoma virus | <molecular biology, virology> Replication defective retrovirus, source of the oncogene v mos, responsible for inducing fibrosarcomas in vivo and transforming cells in culture. (18 Nov 1997) |
| leukemia | <haematology> An acute or chronic disease of unknown cause in man and other warm blooded animals that involves the blood forming organs, is characterised by an abnormal increase in the number of leucocytes in the tissues of the body with or without a corresponding increase of those in the circulating blood and is classified according of the type leucocyte most prominently involved. (18 Nov 1997) |
| moloney leukaemia virus | A murine virus arising during the propagation of s37 mouse sarcoma, and causing lymphoid leukaemia in mice. It also infects rats and newborn hamsters and is apparently transmitted vertically to embryos in utero and through mother's milk. (12 Dec 1998) |
| moloney sarcoma virus | A replication-defective murine sarcoma virus (sarcoma viruses, murine) isolated from a rhabdomyosarcoma by moloney in 1966. (12 Dec 1998) |
| Moloney's virus | A lymphoid leukaemia retrovirus of mice, in the subfamily Oncovirinae, isolated originally during propagation of S 37 mouse sarcoma. (05 Mar 2000) |
| Abelson murine leukaemia virus | A retrovirus belonging to the Type C retrovirus group subfamily (family Oncovirinae) which is associated with leukaemia and produces in vitro transformation of mouse cells. (05 Mar 2000) |
| gastroenteritis virus, murine | A species of the coronavirus genus causing hepatitis in mice. Four strains have been identified as mhv 1, mhv 2, mhv 3, and mhv 4 (also known as jhm, which is neurotropic and causes disseminated encephalomyelitis with demyelination as well as focal liver necrosis). (12 Dec 1998) |
| murine leukaemia virus | <virology> A group of type C retroviruses infecting mice and causing in some strains lymphatic leukaemia after a long latent period. Nearly all are replication competemt and v onc minus. See: Abelson leukaemia virus. (18 Nov 1997) |
| murine sarcoma virus | A seemingly defective retrovirus that produces sarcomas in mice when growing in the presence of a "helper" virus; e.g., mouse leukaemia virus. (05 Mar 2000) |
| theiler's murine encephalomyelitis virus | A species of cardiovirus which causes poliomyelitis in rats. It should not be confused with the strain of encepalomyocarditis virus called encephalomyelitis virus, murine, which is also a cardiovirus. (12 Dec 1998) |
| encephalomyelitis virus, murine | A strain of encephalomyocarditis virus, a species of cardiovirus, usually causing an inapparent intestinal infection in mice. A small number of mice may show signs of flaccid paralysis. (12 Dec 1998) |
| Friend murine leukaemia virus | <virology> Murine leukaemia virus isolated by Charlotte Friend in 1956 whilst attempting to transmit the Erlich ascites tumour by cell free extracts. Causes an unusual erythroblastosis like leukaemia, in which anaemia is accompanied by large numbers of nucleated red cells in blood. does not carry a host derived oncogene, but seems to induce tumours by proviral insertion into specific regions of host genome. (18 Nov 1997) |
| Moloney, John | <person> 20th century U.S. Oncologist. See: Moloney's virus. (05 Mar 2000) |
| Moloney, Paul | <person> Canadian physician, 1870-1939. See: Moloney test. (05 Mar 2000) |