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mixed connective tissue disease (noun) a syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and Raynaud's phenomenon. The disease is differentially characterized by high serum titres of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen (nuclear ribonucleoprotein) and a speckled epidermal nuclear staining pattern on direct immunofluorescence. A more modern term for this condition is the undifferentiated connective tissues disease
Ãâó: www.orgsites.com/fl/adjuvantdisease/_pgg9.php3
mixed connective tissue disease types of autoimmune diseases also known as 'overlap syndromes'.
Ãâó: www.arc.org.uk/about_arth/glossary.htm
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