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G0 quiescent phase of cells leaving the mitotic cycle
MA malignant arrhythmia; management and administration; mandelic acid; masseter; Master of Arts; matern...
MC mass casualties; mast cell; Master of Surgery [Lat. Magister Chirurgiae]; maximum concentration; Med...
MCP maximum closure pressure; maximum contraction pattern; malanocortin receptor; melphalan, cyclophosph...
MF magnetic field; meat free; medium frequency; megafarad; membrane filler; merthiolate-formaldehyde [s...
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MI Mitotic
MAI Mitotic Activity Index
M.I. Mitotic Index
MA Mitotic activity
MA Mitotic apparatus
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CancerWEB ¿µ¿µ ÀÇÇлçÀü ¸ÂÃã °Ë»ö °á°ú : 1 ÆäÀÌÁö: 1
mitotic nondisjunction Failure of the two members of a chromosome pair to separate (disjoin) during mitosis so that both go to one daughter cell and none to the other.
(12 Dec 1998)
CancerWEB ¿µ¿µ ÀÇÇлçÀü À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
meiotic nondisjunction Failure of two memberrs of a chromosome pair to separate (disjoin) during meiosis so that both go to one daughter cell and none to the other. This mechanism is responsible for the extra chromosome 21 in trisomy 21 (down syndrome) and for extra and missing chromosomes causing other birth defects and many spontaneous abortions (miscarriages).
(12 Dec 1998)
primary nondisjunction Nondisjunction occurring in a previously normal cell.
(05 Mar 2000)
secondary nondisjunction Nondisjunction occurring in an aneuploid cell that was the result of a primary nondisjunction.
(05 Mar 2000)
nondisjunction <genetics, molecular biology> Failure of homologous chromosomes or sister chromatids to separate or segregate at meiosis or mitosis respectively. It results in aneuploid cells, where the daughter cell has two chromosomes or two chromatids and the other has none.
Nondisjunction of the X chromosome in Drosophila confirmed the theory of chromosomal inheritance.
(17 Jul 2002)
mitotic Pertaining to mitosis.
(12 Dec 1998)
mitotic apparatus See: mitosis, spindle fibre.
(18 Nov 1997)
mitotic cell selection A drug-free procedure for the selection of mitotic cells from an exponentially growing monolayer.
(09 Oct 1997)
mitotic cycle <cell biology, molecular biology> The sequence of events between mitotic divisions. The cycle is conventionally divided into G0, G1, (G standing for gap), S (synthesis phase during which the DNA is replicated), G2 and M (mitosis).
Cells that will not divide again are considered to be in G0 and the transition from G0 to G1 is thought to commit the cell to completing the cycle and dividing.
(26 Mar 1998)
mitotic death <cell biology> Cells fatally damaged by ionising radiation may not die until the next mitosis, at which point the radiation damage to the DNA becomes evident, particularly when there is fragmentation of chromosomes.
(18 Nov 1997)
mitotic division <cell biology> A method of indirect division of a cell, consisting of a complex of various processes, by means of which the two daughter nuclei normally receive identical complements of the number of chromosomes characteristic of the somatic cells of the species. Mitosis, the process by which the body grows and replaces cells, is divided into four phases.
1. Prophase: formation of paired chromosomes, disappearance of nuclear membrane, appearance of the achromatic spindle, formation of polar bodies.
2. Metaphase: arrangement of chromosomes in the equatorial plane of the central spindle to form the monaster. Chromosomes separate into exactly similar halves.
3. Anaphase: the two groups of daughter chromosomes separate and move along the fibres of the central spindle, each toward one of the asters, forming the diaster.
4. Telophase: the daughter chromosomes resolve themselves into a reticulum and the daughter nuclei are formed, the cytoplasm divides, forming two complete daughter cells.
NOTE: the term mitosis is used interchangeably with cell division, but strictly speaking it refers to nuclear division, whereas cytokinesis refers to division of the cytoplasm. In some cells, as in many fungi and the fertilized eggs of many insects, nuclear division occurs within the cell unaccompanied by division of the cytoplasm and formation of daughter cells.
(13 Nov 1997)
mitotic figure The microscopic appearance of a cell undergoing mitosis; a cell of which the chromosomes are visible by the light microscope.
(05 Mar 2000)
mitotic index <cell biology, molecular biology> The fraction of cells in a sample that are in mitosis. It is a measure of the relative length of the mitotic phase of the cell cycle.
(18 Nov 1997)
mitotic period The period of the cell cycle in which all phases of mitosis occur.
Synonym: M phase.
(05 Mar 2000)
mitotic rate The proportion of cells in a tissue that are undergoing mitosis, expressed as a mitotic index or, roughly, as the number of cells in mitosis in each microscopic high-power field in tissue sections.
(05 Mar 2000)
mitotic recombination <genetics, molecular biology> Somatic crossing over. Crossing over can occur between homologous chromosomes during mitosis, but is very rare because the chromosomes do not normally pair. When it occurs it can lead to new combinations of previously linked genes. Although infrequent, mitotic recombination has been utilised for genetic analysis in Aspergillus and in studies on developmental compartments in Drosophila where the frequency of mitotic recombination can be increased by X irradiation.
(18 Nov 1997)
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