| SSC | single-strand conformational [analysis]; sister strand crossover; somatosensory cortex; standard sal... |
|---|---|
| G0 | quiescent phase of cells leaving the mitotic cycle |
| MA | malignant arrhythmia; management and administration; mandelic acid; masseter; Master of Arts; matern... |
| MC | mass casualties; mast cell; Master of Surgery [Lat. Magister Chirurgiae]; maximum concentration; Med... |
| MCP | maximum closure pressure; maximum contraction pattern; malanocortin receptor; melphalan, cyclophosph... |
| MI | Mitotic |
|---|---|
| MAI | Mitotic Activity Index |
| M.I. | Mitotic Index |
| MA | Mitotic activity |
| MA | Mitotic apparatus |
| crossover fixation | <molecular biology> The addition of extra copies of segments of DNA on the same strand by unequal crossing over during meiosis. An explanation for the existence of satellite DNA, which are highly-repeated, non-transcribed sequences of DNA with no clear function. An alternative explanation to saltatory replication. (03 Jul 1999) |
|---|---|
| crossover study | <statistics> A study that compares two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. Usually refers to a study in which the subject is switched from the experimental to the control procedure (or vice versa). In the case of two treatments, a and b, half the subjects are randomly allocated to receive these in the order a, b and half to receive them in the order b, a. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. With this type of study, every patient serves as his or her own control. (21 Jun 2000) |
| study, crossover | A type of clinical trial in which the study subjects receive each treatment in a random order. In this type of study, every patient serves as his or her own control. (12 Dec 1998) |
| double crossover | <genetics, molecular biology> Two events of recombination occuring on the same chromosome. (09 Oct 1997) |
| mitotic | Pertaining to mitosis. (12 Dec 1998) |
| mitotic apparatus | See: mitosis, spindle fibre. (18 Nov 1997) |
| mitotic cell selection | A drug-free procedure for the selection of mitotic cells from an exponentially growing monolayer. (09 Oct 1997) |
| mitotic cycle | <cell biology, molecular biology> The sequence of events between mitotic divisions. The cycle is conventionally divided into G0, G1, (G standing for gap), S (synthesis phase during which the DNA is replicated), G2 and M (mitosis). Cells that will not divide again are considered to be in G0 and the transition from G0 to G1 is thought to commit the cell to completing the cycle and dividing. (26 Mar 1998) |
| mitotic death | <cell biology> Cells fatally damaged by ionising radiation may not die until the next mitosis, at which point the radiation damage to the DNA becomes evident, particularly when there is fragmentation of chromosomes. (18 Nov 1997) |
| mitotic division | <cell biology> A method of indirect division of a cell, consisting of a complex of various processes, by means of which the two daughter nuclei normally receive identical complements of the number of chromosomes characteristic of the somatic cells of the species. Mitosis, the process by which the body grows and replaces cells, is divided into four phases. 1. Prophase: formation of paired chromosomes, disappearance of nuclear membrane, appearance of the achromatic spindle, formation of polar bodies. 2. Metaphase: arrangement of chromosomes in the equatorial plane of the central spindle to form the monaster. Chromosomes separate into exactly similar halves. 3. Anaphase: the two groups of daughter chromosomes separate and move along the fibres of the central spindle, each toward one of the asters, forming the diaster. 4. Telophase: the daughter chromosomes resolve themselves into a reticulum and the daughter nuclei are formed, the cytoplasm divides, forming two complete daughter cells. NOTE: the term mitosis is used interchangeably with cell division, but strictly speaking it refers to nuclear division, whereas cytokinesis refers to division of the cytoplasm. In some cells, as in many fungi and the fertilized eggs of many insects, nuclear division occurs within the cell unaccompanied by division of the cytoplasm and formation of daughter cells. (13 Nov 1997) |
| mitotic figure | The microscopic appearance of a cell undergoing mitosis; a cell of which the chromosomes are visible by the light microscope. (05 Mar 2000) |
| mitotic index | <cell biology, molecular biology> The fraction of cells in a sample that are in mitosis. It is a measure of the relative length of the mitotic phase of the cell cycle. (18 Nov 1997) |
| mitotic nondisjunction | Failure of the two members of a chromosome pair to separate (disjoin) during mitosis so that both go to one daughter cell and none to the other. (12 Dec 1998) |
| mitotic period | The period of the cell cycle in which all phases of mitosis occur. Synonym: M phase. (05 Mar 2000) |
| mitotic rate | The proportion of cells in a tissue that are undergoing mitosis, expressed as a mitotic index or, roughly, as the number of cells in mitosis in each microscopic high-power field in tissue sections. (05 Mar 2000) |
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