| AMA | 1) Anti-Mitochondrial Antibodies 2) American Medical Association |
|---|---|
| MELAS Syndrome | 1. Mitochondrial Encephalomyopathy 2. Lactic Acidosis 3. S... |
| GOTM | glutamic-oxaloacetic transaminase, mitochondrial |
| LIMM | lethal infantile mitochondrial myopathy |
| MA | malignant arrhythmia; management and administration; mandelic acid; masseter; Master of Arts; matern... |
| AMA | Anti-mitochondrial antibodies |
|---|---|
| AMA | Anti-mitochondrial autoantibodies |
| Mt | Mitochondrial |
| m | Mitochondrial |
| mt DNA | Mitochondrial DNA |
| malate-aspartate shuttle | A mechanism for the transfer of NADH reducing equivalents from the cytosol into the mitochondria using two isozymes of malate dehydrogenase and aspartate transaminase. (05 Mar 2000) |
|---|---|
| glycerophosphate shuttle | A mechanism for the transfer of reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise glycerol 3-phosphate in the cytosol; this compound is then transported into the mitochondria where it is converted to dihydroxyacetone phosphate (DHAP) using FAD; DHAP then returns to the cytosol to complete the cycle; found in brain tissue, brown adipose tissue, and white muscle. (05 Mar 2000) |
| shuttle | 1. An instrument used in weaving for passing or shooting the thread of the woof from one side of the cloth to the other between the threads of the warp. "Like shuttles through the loom, so swiftly glide My feathered hours." (Sandys) 2. The sliding thread holder in a sewing machine, which carries the lower thread through a loop of the upper thread, to make a lock stitch. 3. A shutter, as for a channel for molten metal. Shuttle box, any one of numerous species of marine gastropods of the genus Volva, or Radius, having a smooth, spindle-shaped shell prolonged into a channel at each end. Origin: Also shittle, OE. Schitel, scytyl, schetyl; cf. OE. Schitel a bolt of a door, AS. Scyttes; all from AS. Sceotan to shoot; akin to Dan. Skyttel, skytte, shuttle, dial. Sw. Skyttel, skottel. See Shoot, and cf. Shittle, Skittles. Source: Websters Dictionary (01 Mar 1998) |
| shuttle flow | <cell biology> Bulk flow of the cytoplasm of cells. most conspicuous in large cells such as amoebae and the internodal cells of Chara where the rate of movement may be as high as 100 m/sec. See: cyclosis. (18 Nov 1997) |
| shuttle vector | <molecular biology> Cloning vector that replicate in cells of more than one organism, for example E. Coli and yeast. This combination allows DNA from yeast to be grown in E. Coli and tested directly for complementation in yeast. Shuttle vectors are constructed so that they have the origins of replication of the various hosts. (18 Nov 1997) |
| anti-mitochondrial antibodies | A special serologic test that measures the level of antibodies to a particular portion of a cell (mitochondria). (27 Sep 1997) |
| bovine mitochondrial endonuclease | <enzyme> Dimer of 29kda peptide; prefers a conserved sequence in the displacement loop region of mitochondrial DNA; nicks double-stranded DNA and fragments single-stranded DNA Registry number: EC 3.1.21.- (26 Jun 1999) |
| genome, mitochondrial | The genetic information contained in the circular chromosome of the mitochondrion, a structure located outside the nucleus in the cytoplasm of the cell. The mitochondrial genome and the chromosomal (nuclear) genome together constitute the entire genome. (12 Dec 1998) |
| mitochondrial | Referring to mitochondria. (12 Dec 1998) |
| mitochondrial chromosome | The DNA component of mitochondria, the chief function of which is synthesis of adenosine triphosphate and the management of cellular energy; the chromosome contains some 16,000 base pairs arranged in a circle. The inheritance is matrilineal, and the mutation rate is unusually high; since each cell contains thousands of copies a mutant form may assume an almost continuous gradation as in a galtonian process. Most of the mutations known have their impact on the respiratory chain. (05 Mar 2000) |
| mitochondrial disease | <disease, neurology> An illnesse, frequently neurological, which can be ascribed to defects in mitochondrial function. If the defect is in the mitochondrial rather than the nuclear genome unusual patterns of inheritance can be observed. (18 Nov 1997) |
| mitochondrial encephalomyopathies | Brain diseases associated with disease of the muscles, accompanied by morphological changes in the muscle mitochondria and their metabolism. The mitochondrial encephalopathies are often multisystemic and vary considerably in age at onset, distribution of weakness, severity, and course. Mitochondrial cytochrome c oxidase deficiency appears to be implicated and often several mitochondrial enzymes are affected in the same patient. The brain lesions can be said to be clinical and morphological expressions of a mitochondrial defect. (12 Dec 1998) |
| mitochondrial gene | A functioning gene located not in the nucleus of a cell but in the mitochondrial chromosome. (05 Mar 2000) |
| mitochondrial genome | All of the DNA in the mitochondrial chromosome. (12 Dec 1998) |
| mitochondrial inheritance | The inheritance of a trait encoded in the mitochondrial genome. Because of the oddities of mitochondria, mitochondrial inheritance does not obey the classic rules of genetics. Persons with a mitochondrial disease may be male or female but they are always related in the maternal line and no male with the disease can transmit it to his children. (12 Dec 1998) |
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