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minimal reacting dose The minimal dose of a toxic substance causing a reaction, as manifested in the skin of a series of susceptible test animals; the assay is based on the development of a characteristic, minimal but definite, "standard," focal inflammation (congestion and oedema, induration, degenerative changes, and desquamation of epidermal cells).
(05 Mar 2000)
minimum <statistics> The smallest amount or lowest limit.
(12 Jan 1998)
minimum light Threshold of visual sensation, the minimal light intensity evoking a visual sensation.
Synonym: achromatic threshold, minimum light threshold.
(05 Mar 2000)
minimum light threshold Threshold of visual sensation, the minimal light intensity evoking a visual sensation.
Synonym: achromatic threshold, minimum light threshold.
(05 Mar 2000)
minimum protein requirement <nutrition> The age-dependent amount of protein required daily in the diet.
(05 Mar 2000)
minimum temperature In bacteriology, denoting a temperature below which growth will not take place.
(05 Mar 2000)
Eagle's minimum essential medium A tissue culture medium similar to Eagle's basal medium but with different amounts and a few exclusions (e.g., antibiotics and phenol red).
(05 Mar 2000)
law of the minimum Growth and development of plants and animals are determined by the availability of that essential nutrient which is present in the smallest amount.
(05 Mar 2000)
cross-reacting agglutinin An immune agglutinin specific for a group antigen.
Synonym: cross-reacting agglutinin.
(05 Mar 2000)
cross-reacting antibody <immunology> Antibody specific for group antigens, i.e., those with identical functional groups, antibody for antigens that have functional groups of closely similar, but not identical, chemical structure.
(05 Mar 2000)
cross-reacting material <haematology> A substance sufficiently different from a reference substance (R) to have a perceptibly different function from R but sufficiently similar to R that it reacts with anti-R antibodies; e.g., mutant factor VIII may be defective or even inert in coagulation and yet be immunologically identified as factor VIII.
(05 Mar 2000)
slow-reacting factor of anaphylaxis Slow-reacting substance of anaphylaxis (SRS-A), a leukotriene of low molecular weight which is released in anaphylactic shock and produces slower and more prolonged contraction of muscle than does histamine; it is active in the presence of antihistamines (but not epinephrine) and seems not to occur preformed in mast cells, but as a result of an antigen-antibody reaction on the granules.
Compare: peptidyl leukotrienes.
Synonym: slow-reacting factor of anaphylaxis.
(05 Mar 2000)
slow-reacting substance Slow-reacting substance of anaphylaxis (SRS-A), a leukotriene of low molecular weight which is released in anaphylactic shock and produces slower and more prolonged contraction of muscle than does histamine; it is active in the presence of antihistamines (but not epinephrine) and seems not to occur preformed in mast cells, but as a result of an antigen-antibody reaction on the granules.
Compare: peptidyl leukotrienes.
Synonym: slow-reacting factor of anaphylaxis.
(05 Mar 2000)
slow reacting substance of anaphylaxis <immunology> Potent bronchoconstrictor and inflammatory agent released by mast cells, an important mediator of allergic bronchial asthma.
A mixture of three leukotrienes (LTC4 mainly, LTD4 and LTE4)
(18 Nov 1997)
direct reacting bilirubin The fraction of serum bilirubin which has been conjugated with glucuronic acid in the liver cell to form bilirubin diglucuronide; so called because it reacts directly with the Ehrlich diazo reagent; increased levels are found in hepatobiliary diseases, especially of the obstructive variety.
Synonym: conjugated bilirubin.
(05 Mar 2000)
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