| nicotinamide | <biochemistry> Member of the water soluble B vitamin group, used in the production of fatty acids, steroids and cholesterol, deficiency is known as pellagra. Has cholesterol-lowering and vasodilating properties. (27 Sep 1997) |
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| nicotinamide adenine dinucleotide | <enzyme> Coenzymes that act as electron and hydrogen carriers in some oxidation-reduction reactions. (09 Oct 1997) |
| nicotinamide adenine dinucleotide phosphate | See: NADP. (18 Nov 1997) |
| nicotinamide methyltransferase | <enzyme> Catalyses reversibly the methylation of nicotinamide in the presence of s-adenosylmethionine to yield 1-methylnicotinamide and s-adenosylhomocysteine Registry number: EC 2.1.1.1 Synonym: nicotinamide methylase, nicotinamide-s-adenosylmethionine methyltransferase (26 Jun 1999) |
| nicotinamide mononucleotide | <chemical> 3-carbamoyl-1-beta-d-ribofuranosyl pyridinium hydroxide-5'phosphate, inner salt. A nucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of d-ribose. Synonym: nicotinamide ribonucleotide; nmn. Chemical name: Pyridinium, 3-(aminocarbonyl)-1-(5-O-phosphono-beta-D-ribofuranosyl)-, inner salt (12 Dec 1998) |
| nicotinamide-nucleotide adenylyltransferase | <enzyme> An enzyme that catalyses reversibly the transfer of the adenylyl moiety of ATP to the phosphoryl group of nmn to form NAD+ and pyrophosphate. The enzyme is found predominantly in the nuclei and catalyses the final reaction in the major pathway for the biosynthesis of NAD in mammals. Chemical name: ATP:nicotinamide-nucleotide adenylyltransferase Registry number: EC 2.7.7.1 (12 Dec 1998) |
| nicotinamide phosphoribosyltransferase | <enzyme> Utilises nicotinamide, mg(2+), prpp and ATP Registry number: EC 2.4.2.12 Synonym: nmn pyrophosphorylase (26 Jun 1999) |
| nicotinamide riboside kinase | <enzyme> Phosphorylates 3-deazaguanosine and tiazofurin Registry number: EC 2.7.1.- (26 Jun 1999) |
| active methyl | A methyl group attached to a quaternary ammonium ion or a tertiary sulfonium ion that can take part in transmethylation reactions; e.g., methyl groups in choline and in S-adenosyl-l-methionine, which are thus methyl donors. (05 Mar 2000) |
| aklanonic acid methyl ester cyclase | <enzyme> Catalyses the formation of aklaviketone from aklanonic acid methyl ester; involved in daunomycin biosynthesis; see also daunorubicin-doxorubicin polyketide synthase Registry number: EC 5.- Synonym: aame cyclase, daud protein, daud gene product, dnrd protein, dnrd gene product (26 Jun 1999) |
| alpha-(4-O-methyl)-D-glucuronidase | <enzyme> Removes 4-o-methyl-glucopyranosyl uronic acid residues from the 2-position of fungal cell wall xylans Registry number: EC 3.2.1.- Synonym: 4-o-methyl-glucuronidase (26 Jun 1999) |
| alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid | <chemical> Alpha-amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid. An ibotenic acid homolog and glutamate agonist. The compound is the defining agonist for the ampa subtype of glutamate receptors (receptors, ampa). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies. Pharmacological action: excitatory amino acid agonists. Chemical name: 4-Isoxazolepropanoic acid, alpha-amino-2,3-dihydro-5-methyl-3-oxo- (12 Dec 1998) |
| alpha methyl dopa | <drug> An antihypertensive drug, preferred in pregnant patients. (18 Nov 1997) |
| angular methyl | A methyl group attached to carbon 10 (between rings A and B) or to carbon 13 (between rings C and D) of the steroid nucleus. (05 Mar 2000) |
| bevonium methyl sulfate | 2-(hydroxymethyl)-1,1-dimethylpiperidinium methyl sulfate benzylate;an anticholinergic agent. Synonym: pyribenzyl methyl sulfate. (05 Mar 2000) |