metab : KMLE 의학 검색 엔진 - 의학사전, 의학용어, 의학약어, 의학논문, 약품/의약품 검색

MeSH(Medical Subject Headings) 맞춤 검색 (http://www.nlm.nih.gov) 결과 : 5 페이지: 1

Metabolic Clearance Rate - 새창 Volume of biological fluid completely cleared of drug metabolites as measured in unit time. Elimination occurs as a result of metabolic processes in the kidney, liver, saliva, sweat, intestine, heart, brain, or other site.
Synonyms : Clearance Rate, Metabolic, Clearance Rates, Metabolic, Metabolic Clearance Rates, Rate, Metabolic Clearance, Rates, Metabolic Clearance
Metabolic Detoxication, Drug - 새창 Reduction of pharmacologic activity or toxicity of a drug or other foreign substance by a living system, usually by enzymatic action. It includes those metabolic transformations that make the substance more soluble for faster renal excretion.
Synonyms : Detoxification, Drug, Metabolic, Metabolic Detoxification, Drug, Detoxication, Drug Metabolic, Detoxication, Metabolic Drug, Detoxications, Drug Metabolic, Detoxications, Metabolic Drug, Detoxification, Drug Metabolic, Detoxifications, Drug Metabolic
Metabolic Detoxication, Phase I - 새창 Functionalization of exogenous substances to prepare them for conjugation in PHASE II DETOXIFICATION. Phase I enzymes include CYTOCHROME P450 enzymes and some OXIDOREDUCTASES. Excess induction of phase I over phase II detoxification leads to higher levels of FREE RADICALS that can induce CANCER and other cell damage. Induction or antagonism of phase I detoxication is the basis of a number of DRUG INTERACTIONS.
Synonyms : Metabolic Detoxication, Oxidative, Metabolic Detoxification, Phase I, Phase I Detoxification, Detoxication, Oxidative Metabolic, Detoxications, Oxidative Metabolic, Detoxification, Phase I, Detoxifications, Phase I, Metabolic Detoxications, Oxidative
Metabolic Detoxication, Phase II - 새창 Conjugation of exogenous substances with various hydrophilic substituents to form water soluble products that are excretable in URINE. Phase II modifications include GLUTATHIONE; ACYLATION; and AMINATION. Phase II enzymes include GLUTATHIONE TRANSFERASE and GLUCURONOSYLTRANSFERASE. In a sense these reactions detoxify phase I reaction products.
Synonyms : Metabolic Detoxication, Conjugative, Metabolic Detoxification, Phase II, Phase II Detoxification, Conjugative Metabolic Detoxication, Conjugative Metabolic Detoxications, Detoxication, Conjugative Metabolic, Detoxications, Conjugative Metabolic
Metabolic Diseases - 새창 Generic term for diseases caused by an abnormal metabolic process. It can be congenital due to inherited enzyme abnormality (METABOLISM, INBORN ERRORS) or acquired due to disease of an endocrine organ or failure of a metabolically important organ such as the liver. (Stedman, 26th ed)
Synonyms : Diseases, Metabolic, Disease, Metabolic, Metabolic Disease, Thesaurismoses