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maximum permissible dose <radiobiology> Defined by the International Commission on Radiological Protection as the greatest dose of radiation which, in the light of present knowledge, is not expected to cause detectable bodily injury to a person at any time during his lifetime.
This dose has been reduced with each Commission report. The MPD is given in terms of acute or chronic exposure of the whole body or of organs, systems, or regions of the body, and differs for persons who are occupationally exposed versus the public at large.
(05 Mar 2000)
high dose tolerance The induction of tolerance by exposure to high doses of antigen.
(05 Mar 2000)
immunologic high dose tolerance Induction of tolerance by exposure to large amounts of protein antigens.
(05 Mar 2000)
tolerance dose The largest dose of a remedy that can be accepted without the production of injurious symptoms.
(05 Mar 2000)
maximum 1. The greatest possible or actual effect or quantity.
2. The acme of a disease or process.
(18 Nov 1997)
maximum breathing capacity The volume of air breathed when an individual breathes as deeply and as quickly as possible for a given time (e.g., 15 sec.).
Synonym: maximum breathing capacity.
(05 Mar 2000)
maximum occipital point The point on the squama of the occipital bone farthest from the glabella.
(05 Mar 2000)
maximum permissible exposure level The highest level of exposure to a substance, usually noxious, in the environment or during diagnostic and therapeutic procedures, that a body can tolerate without injury.
(12 Dec 1998)
maximum temperature In bacteriology, denoting a temperature above which growth will not take place.
(05 Mar 2000)
maximum urea clearance The urea clearance when the urine flow exceeds 2 ml/min; normal value is about 75 ml blood/min per 1.73 m2 body surface area.
(05 Mar 2000)
maximum velocity The maximum rate of an enzyme-catalyzed reaction that can be achieved by progressively increasing the substrate concentration at a given enzyme concentration; in cases of substrate inhibition, Vmax is an extrapolated value in the absence of such inhibition; Cf.: Michaelis-Menten equation.
The maximum initial rate of shortening of a myocardial fibre that can be obtained under zero load; used to evaluate the contractility of the fibre.
(05 Mar 2000)
maximum voluntary ventilation The volume of air breathed when an individual breathes as deeply and as quickly as possible for a given time (e.g., 15 sec.).
Synonym: maximum breathing capacity.
(05 Mar 2000)
tubular maximum transport maximum
acoustic tolerance The maximum sound pressure level that can be experienced without producing pain or permanent defect of hearing in a normal individual.
(05 Mar 2000)
bile acid tolerance test A sensitive test of hepatic dysfunction; following oral administration of labelled or unlabelled bile acid, the measured fractional disappearance rate or 10-minute retention is measured.
(05 Mar 2000)
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