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matching of controls In medical research, ensuring that the group of actively treated subjects has as many relevant similarities as possible to a group of untreated or placebo-treated persons. Matching subjects with controls increases the likeli
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matching 1. comparison and selection of objects having similar or identical characteristics.  2. the selection of compatible donors and recipients for transfusion or transplantation. See also typing.  3. the selection of subjects for clinical trials or other studies so that the different groups being compared are similar in specified characteristics, e.g., age, sex, or race, in order to reduce bias and error caused by comparison of dissimilar groups. Matching may be on an individual (matched pairs) or a group-wide basis.
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