| 영문 | growth hormone | 한글 | 성장호르몬 |
|---|---|---|---|
| 설명 | 뇌하수체 전엽에서 분비되는 호르몬중 하나로서 시상하부의 성장호르몬방출 호르몬에 의해 분비가 자극되며 소마토스타틴(somatostatin: 이자에서 분비되며, 성장호르몬에 반대되는 작용을 함)에 의해 분비가 억제된다. 성장 호르몬 방출 호르몬은 도파민(dopamine)으로 알려져 있다. 성장 호르몬은 세포의 성장을 촉진시키며 특히 골의 성장을 자극하는데 그 작용은 직접 세포에 작용하는 것이 아니라 간과 근육에 작용하여 그곳에서 소마토메딘을 생성하며 이 소마토메딘이 세포의 성장을 촉진시킨다. 한편 성장 호르몬은 성장에 필요한 단백질 합성을 항진시키고 에너지는 지방을 이용하여 얻게하므로 지방이용호르몬이라고도 불린다. 성장 호르몬이 과다 분비되면 거인증, 말단비대증이 유발되며 성장 호르몬이 결핍되면 성장부진이 온다. |
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| 영문 | growth factor | 한글 | 성장인자 |
|---|---|---|---|
| 설명 | 세포의 분화 및 성장에 관여하는 단백질. 성장인자는 정상 세포주기에 필수적이기 때문에 동물의 생명에 중대한 요소가 된다. 무엇보다도 성장인자는 태아의 발육을 조정하고 조직의 유지 및 보수에 중대한 역할을 하며, 혈구의 생성을 자극한다. 또한 암의 진행과정에도 관여한다. |
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| 영문 | mammary papilla, nipple | 한글 | 유두, 젖꼭지 |
|---|---|---|---|
| 설명 | 젖샘에서 만들어진 모유가 나오는 통로에 해당. |
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| 영문 | mammary glands | 한글 | 젖샘, 유선 |
|---|---|---|---|
| 설명 | 정상적으로 아기를 낳은 산모에서는 뇌에서 젖분비호르몬(prolactin)의 분비가 증가하여 젖샘에서 젖을 만들게 된다. 이 때 젖의 분비를 촉진시키는 것으로는 아기가 젖을 빠는 행위 등이 있으며, 젖샘에서 생산된 모유는 젖샘관을 거쳐 젖꼭지를 통해 밖으로 나가게 된다. |
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| MTV | mammary tumor virus; metatarsus varus; mouse mammary tumor virus |
|---|---|
| BPTI | basic pancreatic trypsin inhibitor; basic polyvalent trypsin inhibitor; bovine pancreatic trypsin in... |
| PI | first meiotic prophase; isoelectric point; pacing impulse; package insert; pancreatic insufficiency;... |
| HCG, hCG | Human Chorionic Gonadotropin; 사람융모성성선자극호르몬 1. Placental Glycoprotein Hormone &nbs... |
| NG | nasogastric; neoplastic growth; new growth; nitroglycerin; nodose ganglion; no growth; not given |
| MDGI | Mammary derived growth inhibitor |
|---|---|
| PDGF | Anti-platelet-derived growth factor |
| EDGF | Eye Derived Growth Factor |
| PDGF | Plateled derived growth factor |
| PDGF BB | Platelet Derived Growth Factor |
IGF-II : insulin like growth factor-II의 약자. 많은 장기와 조직에 작용하여 단백 합성과 DNA, RNA의 합성을 증가시켜 세포의 수와 양을 증가
| mammary derived growth inhibitor | Fatty acid binding protein that inhibits proliferation of mammary carcinoma cells. (18 Nov 1997) |
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| brain-derived growth factor | <growth factor> Small basic protein purified from pig brain, a member of the family of neurotrophic factors that also includes Nerve Growth Factor and neurotrophin 3. In contrast to nerve growth factor, brain-derived neurotrophic factor is predominanantly (though not exclusively) localised in the CNS. It supports the survival of primary sensory neurons originating from the neural crest and ectodermal placodes that are not responsive to NGF. In the brain brain-derived neurotrophic factor has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons. Acronym: BDGF (12 Dec 1998) |
|---|---|
| receptors, platelet-derived growth factor | Specific molecular sites or structures on cell membranes that react with platelet-derived growth factor, its analogs, or antagonists, to elicit or to inhibit the specific response of the cell to this factor. Pdgf binds with different affinities and specificities to two structurally related receptors, the alpha-receptor and the beta-receptor. Both of these receptors are transmembrane proteins with an intracellular, ligand-stimulatable protein kinase domain. (12 Dec 1998) |
| platelet-derived growth factor | <growth factor> The major mitogen in serum for growth in culture of cells of connective tissue origin. It consists of 2 different but homologous polypeptides A and B (~30,000 D) linked by disulphide bonds. Believed to play a role in wound healing. It is carried in the alpha-granules of platelets and is released when platelets adhere to traumatised tissues. Connective tissue cells near the traumatised region respond by initiating the process of replication. The B chain is almost identical in sequence to p28sis, the transforming protein of simian sarcoma virus, that can transform only those cells that express receptors for platelet derived growth factor, suggesting that transformation is caused by autocrine stimulation. The receptor is a tyrosine kinase. Acronym: PDGF (12 Dec 1998) |
| schwannoma derived growth factor | <growth factor> A growth factor containing an EGF like domain, mitogenic for astrocytes, Schwann cells and fibroblasts. (18 Nov 1997) |
| endothelium-derived growth factor synthase | <enzyme> Converts l-arginine to a smooth muscle relaxing factor and stimulates the formation of cyclic-GMP Registry number: EC 1.5.1.- Synonym: edrf synthase (26 Jun 1999) |
| brain-derived neurotrophic factor | <growth factor> Small basic protein purified from pig brain, a member of the family of neurotrophic factors that also includes Nerve Growth Factor and neurotrophin 3. In contrast to nerve growth factor, brain-derived neurotrophic factor is predominanantly (though not exclusively) localised in the CNS. It supports the survival of primary sensory neurons originating from the neural crest and ectodermal placodes that are not responsive to NGF. In the brain brain-derived neurotrophic factor has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons. Acronym: BDGF (12 Dec 1998) |
| refuse-derived fuel | (RDF) Fuel prepared from municipal solid waste. Noncombustible materials such as rocks, glass, and metals are removed, and the remaining combustible portion of the solid waste is choped or shreaded. RDF facilities process between 100 and 3000 tons of MSW per day. (05 Dec 1998) |
| monocyte derived neutrophil chemotactic factor | <cytokine> A cytokine that activates neutrophils and attracts neutrophils and T-lymphocytes. It is released by several cell types including monocytes, macrophages, T-lymphocytes, fibroblasts, endothelial cells, and keratinocytes by an inflammatory stimulus. Il-8 is a member of the beta-thromboglobulin superfamily and structurally related to platelet factor 4. Acronym: IL-8 (12 Dec 1998) |
| derived protein | A derivative of protein effected by chemical change, e.g., hydrolysis. (05 Mar 2000) |
| oxygen derived free radicals | An atom or atom group having an unpaired electron on an oxygen atom, typically derived from molecular oxygen. For example, one-electron reduction of O2 produces the superoxide radical, O2-; other examples include the hydroperoxyl radical (HOO-), the hydroxyl radical (HO-), and nitric oxide (NO-). (05 Mar 2000) |
| thymus derived lymphocyte | <haematology, immunology> A class of lymphocytes, so called because they are derived from the thymus and have been through thymic processing. Involved primarily in controlling cell-mediated immune reactions and in the control of B-cell development. The T-cells coordinate the immune system by secreting lymphokine hormones. There are 3 fundamentally different types of t cells : helper, killer, and suppressor. Each has many subdivisions. T-cells are also called t lymphocytes. They bear T-cell antigen receptors (CD3) and lack Fc or C3b receptors. Major T-cell subsets are CD4 (mainly helper cells) and CD8 (mostly cytotoxic or suppressor T-cells). Uncontrolled proliferation of this type of cell gives rise to T-cell leukaemia/lymphoma. (21 Jun 1999) |
| endothelium derived relaxation factor | <biochemistry> This compound is produced from L arginine by the enzyme nitric oxide synthase. Acts as a potent vasorelaxant via elevation of intracellular cGMP in vascular smooth muscle. Synthesis of nitric oxide is not confined to endothelium, isoforms of nitric oxide synthase are also found in brain, neutrophils and platelets. Synonym: endothelium derived relaxation factor. Acronym: NO (29 Dec 1997) |
| endothelium-derived relaxing factor | A labile humoral agent released by the vascular endothelium that mediates the relaxation induced by some vasodilators such as acetylcholine and bradykinin. Edrf also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. These actions are believed to be mediated through stimulation of guanylate cyclase and the consequent elevation of cyclic guanosine 3',5'-monophosphate. Edrf is thought to be nitric oxide or a ready source of it. The factor is believed to be unstable and acts only locally in vivo. (12 Dec 1998) |
| body of mammary gland | The principal part of the breast, consisting of glandular tissue and its supporting fibrous tissue. It forms a conical mass converging toward the nipple and is surrounded by adipose tissue. Synonym: corpus mammae. (05 Mar 2000) |
| paget's disease, mammary | An intraductal carcinoma of the breast extending to involve the nipple and areola, characterised clinically by eczema-like inflammatory skin changes and histologically by infiltration of the dermis by malignant cells (paget's cells). (12 Dec 1998) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|